| Catalog No. | Size | Price (USD) |
| 10587-MM05-A-25 | 25 Tests | $133.30 |
| 10587-MM05-A-100 | 100 Tests | $414.71 |
General Information
| Product name | Anti-Integrin beta 1 Antibody (APC), Mouse Monoclonal |
| Validated applications | FCM (FAQ Protocol) |
| Species reactivity | Reacts with: Human |
| Specificity | Human Integrin beta 1 |
| Immunogen | Recombinant Human Integrin beta 1/ITGB1 Protein (Catalog#10587-H08H1) |
| Preparation | This antibody was produced from a hybridoma resulting from the fusion of a mouse myeloma with B cells obtained from a mouse immunized with purified, recombinant Human Integrin beta 1/ITGB1 (rh Integrin beta 1/ITGB1; Catalog#10587-H08H1; CAA30790.1; Met1-Asp728) and conjugated with APC under optimum conditions, the unreacted APC was removed. |
| Source | Monoclonal Mouse IgG1 Clone #05 |
| Purification | Protein A |
| Formulation | PBS solution containing 0.5% BSA and 0.03%ProClin300 |
| Concentration | 5 μl/Test, 0.1 mg/ml |
| Conjugate | APC |
| Form | Liquid |
| Shipping | This antibody is shipped as liquid solution at ambient temperature. Upon receipt, store it immediately at the temperature recommended below. |
| Storage | This antibody can be stored at 2℃-8℃ for twelve months without detectable loss of activity. Protected from prolonged exposure to light. Do not freeze ! |
Synonyms: Anti-CD29 Antibody; Anti-FNRB Antibody; Anti-GPIIA Antibody; Anti-MDF2 Antibody; Anti-MSK12 Antibody; Anti-VLA-BETA Antibody; Anti-VLAB Antibody
Image / Experimental Information
| Image 1 Description | Flow cytometric analysis of Human ITGB1(CD29) expression on human whole blood lymphocytes. Cells were stained with APC-conjugated anti-Human ITGB1(CD29). The fluorescence histograms were derived from gated events with the forward and side light-scatter characteristics of viable lymphocytes. |
| Image 1 Alt Text | Human Integrin beta 1 Flow Cytometry (FC) 21126 |
| Image 1 URL | Source image |
Background Information
| Full Name | integrin, beta 1 (fibronectin receptor, beta polypeptide, antigen CD29 includes MDF2, MSK12) |
| Description | ITGB1 (Integrin Subunit Beta 1) is a Protein Coding gene. This gene encodes a beta subunit, which is a type 1 transmembrane protein of the integrin beta chain family. ITGB1 is a heterodimeric cell-surface receptor involved in cell functions such as proliferation, migration, invasion, and survival. ITGB1 has been recognized to play a major role in tumor growth, invasion, and metastasis. Using luciferase assays, the researcher identified ITGB1 as a direct target of miR-134. ITGB1 is a direct target of miR-493-5p suggesting that ITGB1 and miR-493-5p may have potential prognostic value and may be useful as tumor biomarkers for the diagnosis of NSCLC patients. Diseases associated with ITGB1 include Gallbladder Cancer and Breast Cancer. |
| Research Areas |
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| Related Pathways |
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title: Surface Engineering of HEK293 Cell-Derived Extracellular Vesicles for Improved Pharmacokinetic Profile and Targeted Delivery of IL-12 for the Treatment of Hepatocellular Carcinoma
authors: Jing Zhang; Haijing Song; ...; Haifeng Song
journal: International Journal of Nanomedicine
date: 2023-01-13
pmid: 36660339
doi: 10.2147/IJN.S388916
pmcid: 9844138
cited_by_count: 24
techniques: Activity Assay; Binding Assay; CRISPR; Clinical Proteomics; Concentration Assay; Control; Cytometry; Derivative Assay; Disruption; Expressing; Flow Cytometry; Fluorescence; In Vivo; Incubation; Infection; Injection; Knock-Out; Labeling; Luciferase; Membrane; Plasmid Preparation; Recombinant; Single Cell; Staining; Suspension; Western Blot
bioz_score: 91
-MM05-APC-Lymphocytes.png){kind=link}