| Catalog No. | Size | Price (USD) |
| 207352-T10-50 | 50 µL | $147.96 |
| 207352-T10-100 | 100 µL | $251.64 |
| 207352-T10-200 | 200 µL | $355.32 |
General Information
| Product name | Anti-KLF6 Antibody, Rabbit Polyclonal |
| Validated applications | IHC-P (FAQ Protocol), ICC/IF (FAQ Protocol) |
| Species reactivity | Reacts with: Human |
| Specificity | Human KLF6 |
| Immunogen | E. coli-derived Human KLF6 fragment |
| Preparation | Produced in rabbits immunized with E. coli-derived Human KLF6 fragment, and purified by antigen affinity chromatography. |
| Source | Polyclonal Rabbit IgG |
| Purification | Protein A & Antigen Affinity |
| Formulation | PBS, pH7.0 with 0.03% Proclin300 |
| Conjugate | Unconjugated |
| Form | Liquid |
| Shipping | This antibody is shipped as liquid solution at ambient temperature. Upon receipt, store it immediately at the temperature recommended below. |
| Storage | This antibody can be stored at 2℃-8℃ for one month without detectable loss of activity. Antibody products are stable for twelve months from date of receipt when stored at -20℃ to -80℃. Avoid repeated freeze-thaw cycles. |
Synonyms: Anti-BCD1 Antibody; Anti-CBA1 Antibody; Anti-COPEB Antibody; Anti-CPBP Antibody; Anti-GBF Antibody; Anti-PAC1 Antibody; Anti-ST12 Antibody; Anti-ZF9 Antibody
Image / Experimental Information
| Image 1 Description | Immunochemical staining of human KLF6 in human gallbladder with rabbit polyclonal antibody at 1:2000 dilution, formalin-fixed paraffin embedded sections. |
| Image 1 Alt Text | Human KLF6 Immunohistochemistry(IHC) 26468 |
| Image 1 URL | Source image |
| Image 2 Description | Immunochemical staining of human KLF6 in human gallbladder with rabbit polyclonal antibody at 1:2000 dilution, formalin-fixed paraffin embedded sections. |
| Image 2 Alt Text | Human KLF6 Immunofluorescence(IF) 26469 |
| Image 2 URL | Source image |
Background Information
| Full Name | Kruppel-like factor 6 |
| Description | Kruppel like factor 6 (KLF6), a member of the KLF family, which has a classic zinc finger structure, is broadly considered to have anticancer activity. The Krüppel-like zinc finger transcription factor (KLF6) gene encodes a family of proteins generated through alternative splicing involved in the regulation of cancer development and progression. Alternative splicing of the KLF6 gene results in the production of at least four alternatively spliced isoforms. The full-length form of the KLF6 gene is a tumor suppressor gene that is frequently inactivated by loss of heterozygosity (LOH), somatic mutation, and/or decreased expression in human cancer. The transcription factor Krüppel-like factor 6 (KLF6) regulates various cellular functions, such as metabolism, cell proliferation, and differentiation. The transcription factor KLF6 has an essential role in the development and metastasis of multiple human cancers. |
| References |
|
title: Gene expression networks involved in multiple cellular programs coexist in individual hepatocellular cancer cells
authors: Jin Zhao; Ran Lu; ...; Xianming Mo
journal: Heliyon
date: 2023-07-17
doi: 10.1016/j.heliyon.2023.e18305
pmcid: 10393770
cited_by_count: 0
techniques: Expressing; Immunofluorescence; Incubation; Microscopy; Staining
bioz_score: 91
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