Anti-AARSD1 Antibody, Rabbit Polyclonal sinobiological 201256-T36

$143.00
In stock
SKU
201256-T36
Catalog No.SizePrice (USD)
201256-T36-5050 µL$147.96
201256-T36-100100 µL$251.64
201256-T36-200200 µL$355.32

General Information

Product nameAnti-AARSD1 Antibody, Rabbit Polyclonal
Validated applicationsWB (FAQ Protocol), IP (FAQ Protocol)
Species reactivityReacts with: Human
SpecificityHuman AARSD1
ImmunogenE. coli-derived Human AARSD1 fragment
PreparationProduced in rabbits immunized with E. coli-derived Human AARSD1 fragment, and purified by antigen affinity chromatography.
SourcePolyclonal Rabbit IgG
PurificationProtein A & Antigen Affinity
FormulationPBS, pH7.0 with 0.03% Proclin300
ConjugateUnconjugated
FormLiquid
ShippingThis antibody is shipped as liquid solution at ambient temperature. Upon receipt, store it immediately at the temperature recommended below.
StorageThis antibody can be stored at 2℃-8℃ for one month without detectable loss of activity. Antibody products are stable for twelve months from date of receipt when stored at -20℃ to -80℃. Avoid repeated freeze-thaw cycles.

Synonyms: Anti-AlaXp Antibody; Anti-MGC2744 Antibody

Image / Experimental Information

Image 1 DescriptionAnti-AARSD1 rabbit polyclonal antibody at 1:500 dilution Lane A: A549 Whole Cell Lysate Lane B: 293 Whole Cell Lysate Lane C: HepG2 Whole Cell Lysate Lysates/proteins at 30 μg per lane. Secondary Goat Anti-Rabbit IgG (H+L)/HRP at 1/10000 dilution. Developed using the ECL technique. Performed under reducing conditions. Predicted band size:45 kDa Observed band size:48 kDa
Image 1 Alt TextHuman AARSD1 Western blot (WB) 29410
Image 1 URLSource image
Image 2 DescriptionAnti-AARSD1 rabbit polyclonal antibody at 1:500 dilution Lane A: A549 Whole Cell Lysate Lane B: 293 Whole Cell Lysate Lane C: HepG2 Whole Cell Lysate Lysates/proteins at 30 μg per lane. Secondary Goat Anti-Rabbit IgG (H+L)/HRP at 1/10000 dilution. Developed using the ECL technique. Performed under reducing conditions. Predicted band size:45 kDa Observed band size:48 kDa
Image 2 Alt TextHuman AARSD1 Immunoprecipitation(IP) 29411
Image 2 URLSource image

Background Information

Full Namealanyl-tRNA synthetase domain containing 1
DescriptionAARSD1 belongs to the class-II aminoacyl-tRNA synthetase family, Alax-L subfamily. AARSD1 binds 1 zinc ion per subunit functions in trans to edit the amino acid moiety from incorrectly charged tRNA(Ala). Four transcript variants have been described for AARSD1: NM_25267.3, NM_113642.2, NM_1142653.1 and NM_1142654.1. It has been determined that the latter two variants represent a distinct upstream locus, which is now represented by GeneID:1885848 (PTGES3L), while the former two variants represent readthrough transcripts between PTGES3L and this locus (AARSD1). The readthrough locus (PTGES3L-AARSD1) is now represented by GeneID:188585.
References
  1. Tatham MH, et al. (2011) Comparative proteomic analysis identifies a role for SUMO in protein quality control. Oncogene. 19(17):2120-8.
  2. Kim W, et al. (2011) Systematic and quantitative assessment of the ubiquitin-modified proteome. Mol Cell. 44(2):325-40.
  3. Udeshi ND, et al. (2012) Methods for quantification of in vivo changes in protein ubiquitination following proteasome and deubiquitinase inhibition. Mol Cell Proteomics. 11(5):148-59.

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