| Catalog No. | Size | Price (USD) |
| 10254-R102-B-100 | 100 µg | $518.39 |
General Information
| Product name | Recombinant Anti-MMP-8 Antibody (Biotin), Rabbit Monoclonal |
| Validated applications | ELISA (FAQ Protocol) |
| Species reactivity | Reacts with: Human |
| Specificity | Human MMP-8 |
| Immunogen | Recombinant Human MMP-8 / MMP8 Protein (Catalog#10254-H08H) |
| Preparation | This antibody was obtained from a rabbit immunized with purified, recombinant Human MMP-8 / MMP8 (rh MMP-8 / MMP8; Catalog#10254-H08H; NP_002415.1; Met1-Gly467), and then biotinylated. |
| Source | Monoclonal Rabbit IgG Clone #102 |
| Purification | Protein A |
| Formulation | 0.2 μm filtered solution in PBS |
| Conjugate | Biotin |
| Form | Liquid |
| Shipping | This antibody is shipped as liquid solution at ambient temperature. Upon receipt, store it immediately at the temperature recommended below. |
| Storage | This antibody can be stored at 2℃-8℃ for one month without detectable loss of activity. Antibody products are stable for twelve months from date of receipt when stored at -20℃ to -80℃. Preservative-Free. Avoid repeated freeze-thaw cycles. |
Synonyms: Anti-CLG1 Antibody; Anti-HNC Antibody; Anti-MMP-8 Antibody; Anti-PMNL-CL Antibody
Background Information
| Full Name | matrix metallopeptidase 8 |
| Description | Matrix metalloproteinases (MMPs) are a family of zinc-dependent endopeptidases that degrade components of the extracellular matrix (ECM) and play essential roles in various physiological processes such as morphogenesis, differentiation, angiogenesis, and tissue remodeling, as well as pathological processes including inflammation, arthritis, cardiovascular diseases, pulmonary diseases, and tumor invasion. Neutrophil collagenase, also known as Matrix metalloproteinase-8, MMP-8, and CLG1, is a member of the peptidase M1A family. MMP-8 may affect the metastatic behavior of breast cancer cells through protection against lymph node metastasis, underlining the importance of anti-target identification in drug development. MMP-8 in the tumor may have a protective effect against lymph node metastasis. MMP-8 may affect the metastatic behavior of breast cancer cells through protection against lymph node metastasis, underlining the importance of anti-target identification in drug development. MMP-8 participates in wound repair by contributing to the resolution of inflammation and open the possibility to develop new strategies for treating wound healing defects. |
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