Anti-CCDC47 Antibody, Rabbit Polyclonal sinobiological 201332-T32

$243.00
In stock
SKU
201332-T32
Catalog No.SizePrice (USD)
201332-T32-100100 µL$251.64

General Information

Product nameAnti-CCDC47 Antibody, Rabbit Polyclonal
Validated applicationsWB (FAQ Protocol)
Species reactivityReacts with: Human
SpecificityHuman CCDC47
ImmunogenE. coli-derived Human CCDC47 fragment
PreparationProduced in rabbits immunized with E. coli-derived Human CCDC47 fragment, and purified by antigen affinity chromatography.
SourcePolyclonal Rabbit IgG
PurificationProtein A & Antigen Affinity
FormulationPBS, pH7.0 with 0.03% Proclin300
ConjugateUnconjugated
FormLiquid
ShippingThis antibody is shipped as liquid solution at ambient temperature. Upon receipt, store it immediately at the temperature recommended below.
StorageThis antibody can be stored at 2℃-8℃ for one month without detectable loss of activity. Antibody products are stable for twelve months from date of receipt when stored at -20℃ to -80℃. Avoid repeated freeze-thaw cycles.

Synonyms: Anti-GK001 Antibody; Anti-MSTP041 Antibody; Anti-PSEC0077 Antibody; Anti-THNS Antibody

Image / Experimental Information

Image 1 DescriptionAnti-CCDC47 rabbit polyclonal antibody at 1:500 dilution Lane A: Hela Whole Cell Lysate Lane B: U-251MG Whole Cell Lysate Lysates/proteins at 30 μg per lane. Secondary Goat Anti-Rabbit IgG (H+L)/HRP at 1/10000 dilution. Developed using the ECL technique. Performed under reducing conditions. Predicted band size:56 kDa Observed band size:56 kDa
Image 1 Alt TextHuman CCDC47 Western blot (WB) 37458
Image 1 URLSource image

Background Information

Full Namecoiled-coil domain containing 47
DescriptionCCDC47 gene is expressed at high level. The gene contains 16 distinct gt-ag introns. Transcription produces 9 different mRNAs, 6 alternatively spliced variants and 3 unspliced forms. There are 3 probable alternative promotors, 3 non overlapping alternative last exons and 8 validated alternative polyadenylation sites. The mRNAs appear to differ by truncation of the 5' end, truncation of the 3' end, presence or absence of a cassette exon, overlapping exons with different boundaries. Functionally, CCDC47 gene has been proposed to participate in processes such as calcium ion homeostasis, embryo development, ER overload response and post-embryonic development. CCDC47 are expected to have molecular function (calcium ion binding) and to localize in various compartments (membrane, endoplasmic reticulum, integral to membrane, microsome).
References
  1. Danielsen JM, et al. (2011) Mass spectrometric analysis of lysine ubiquitylation reveals promiscuity at site level. Mol Cell Proteomics. 10(3):M110.003590.
  2. Kim W, et al. (2011) Systematic and quantitative assessment of the ubiquitin-modified proteome. Mol Cell. 44(2):325-40.

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