| Catalog No. | Size | Price (USD) |
| 50356-RP01-100 | 100 µL | $147.96 |
| 50356-RP01-200 | 200 µL | $251.64 |
| 50356-RP01-400 | 400 µL | $355.32 |
General Information
| Product name | Anti-ANGPTL4 Antibody, Rabbit Polyclonal |
| Validated applications | ELISA (FAQ Protocol) |
| Species reactivity | Reacts with: Mouse |
| Specificity | Mouse ANGPTL4 |
| Immunogen | Recombinant Mouse ANGPTL4 / angiopoietin-like protein 4 Protein (Catalog#50356-M07H) |
| Preparation | Produced in rabbits immunized with purified, recombinant Mouse ANGPTL4 / angiopoietin-like protein 4 (rM ANGPTL4 / angiopoietin-like protein 4; Catalog#50356-M07H; Q9Z1P8; Lys167-Ser410). Total IgG was purified by Protein A affinity chromatography. |
| Source | Polyclonal Rabbit IgG |
| Purification | Protein A |
| Formulation | 0.2 μm filtered solution in PBS |
| Conjugate | Unconjugated |
| Form | Liquid |
| Shipping | This antibody is shipped as liquid solution at ambient temperature. Upon receipt, store it immediately at the temperature recommended below. |
| Storage | This antibody can be stored at 2℃-8℃ for one month without detectable loss of activity. Antibody products are stable for twelve months from date of receipt when stored at -20℃ to -80℃. Preservative-Free. Avoid repeated freeze-thaw cycles. |
Synonyms: Anti-Angptl4 Antibody; Anti-Arp4 Antibody; Anti-Bk89 Antibody; Anti-Farp Antibody; Anti-Fiaf Antibody; Anti-Hfarp Antibody; Anti-Ng27 Antibody; Anti-Pgar Antibody; Anti-Pgarg Antibody; Anti-Pp1158 Antibody
Background Information
| Full Name | angiopoietin-like 4 |
| Description | ANGPTL4, also known as ANGPTL2, is a protein with hypoxia-induced expression in endothelial cells. It contains 1 fibrinogen C-terminal domain and is expressed at high levels in the placenta, heart, liver, muscle, pancreas and lung but expressed poorly in the brain and kidney. ANGPTL4 inhibits proliferation, migration, and tubule formation of endothelial cells and reduces vascular leakage. It may act as a regulator of angiogenesis and modulate tumorigenesis. It inhibits proliferation, migration, and tubule formation of endothelial cells and reduces vascular leakage. It may also exert a protective function on endothelial cells through an endocrine action. ANGPTL4 is directly involved in regulating glucose homeostasis, lipid metabolism, and insulin sensitivity. In response to hypoxia, the unprocessed form of the protein accumulates in the subendothelial extracellular matrix (ECM). The matrix-associated and immobilized unprocessed form limits the formation of actin stress fibers and focal contacts in the adhering endothelial cells and inhibits their adhesion. It also decreases motility of endothelial cells and inhibits the sprouting and tube formation. |
| References |
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