Anti-CCDC91 Antibody, Rabbit Polyclonal sinobiological 203721-T08

$143.00
In stock
SKU
203721-T08
Catalog No.SizePrice (USD)
203721-T08-5050 µL$147.96
203721-T08-100100 µL$251.64
203721-T08-200200 µL$355.32

General Information

Product nameAnti-CCDC91 Antibody, Rabbit Polyclonal
Validated applicationsIHC-P (FAQ Protocol)
Species reactivityReacts with: Human
SpecificityHuman CCDC91
ImmunogenE. coli-derived Human CCDC91 fragment
PreparationProduced in rabbits immunized with E. coli-derived Human CCDC91 fragment, and purified by antigen affinity chromatography.
SourcePolyclonal Rabbit IgG
PurificationProtein A & Antigen Affinity
FormulationPBS, pH7.0 with 0.03% Proclin300
ConjugateUnconjugated
FormLiquid
ShippingThis antibody is shipped as liquid solution at ambient temperature. Upon receipt, store it immediately at the temperature recommended below.
StorageThis antibody can be stored at 2℃-8℃ for one month without detectable loss of activity. Antibody products are stable for twelve months from date of receipt when stored at -20℃ to -80℃. Avoid repeated freeze-thaw cycles.

Synonyms: Anti-DKFZp779L1558 Antibody; Anti-FLJ11088 Antibody; Anti-GGABP Antibody; Anti-HSD8 Antibody; Anti-p56 Antibody

Image / Experimental Information

Image 1 DescriptionImmunochemical staining of human CCDC91 in human kidney with rabbit polyclonal antibody at 1:100 dilution, formalin-fixed paraffin embedded sections.
Image 1 Alt TextHuman CCDC91 Immunohistochemistry(IHC) 22572
Image 1 URLSource image
Image 2 DescriptionImmunochemical staining of human CCDC91 in human kidney with rabbit polyclonal antibody at 1:100 dilution, formalin-fixed paraffin embedded sections.
Image 2 Alt TextHuman CCDC91 Immunohistochemistry(IHC) 22573
Image 2 URLSource image

Background Information

Full Namecoiled-coil domain containing 91
DescriptionCCDC91 (Coiled-Coil Domain Containing 91, also known as p56 and HSD8) is a Protein Coding gene. The CCDC91 gene, located on 12p11.22, is conserved in chimpanzee, Rhesus monkey, dog, cow, mouse, rat, and chicken. CCDC91 is involved in the regulation of membrane traffic through the trans-Golgi network (TGN), and functions in close cooperation with the GGAs in the sorting of hydrolases to lysosomes. This gene is widely expressed in the testis, thyroid, and other tissues. Diseases associated with CCDC91 include Ossification Of The Posterior Longitudinal Ligament Of Spine and Diffuse Idiopathic Skeletal Hyperostosis. 3 alternatively spliced human isoforms have been reported.
References
  1. Nakajima M, et al. (2014) A genome-wide association study identifies susceptibility loci for ossification of the posterior longitudinal ligament of the spine. Nat Genet 46 (9): 1012-1016.
  2. Lui WW, et al. (2003) Binding partners for the cooh-terminal appendage domains of the ggas and gamma-adaptin. Mol Biol Cell 14 (6): 2385-2398.
  3. Collins BM, et al. (2003) Structural basis for binding of accessory proteins by the appendage domain of ggas. Nat Struct Biol 10 (8): 607-613.

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