| Catalog No. | Size | Price (USD) |
| 50023-R503-50 | 50 µL | $177.58 |
| 50023-R503-100 | 100 µL | $340.51 |
General Information
| Product name | Recombinant Anti-CD14 Antibody, Rabbit Monoclonal |
| Validated applications | FCM (FAQ Protocol) |
| Species reactivity | Reacts with: Mouse |
| Specificity | Mouse CD14 |
| Immunogen | Recombinant Mouse CD14 protein (Catalog#50023-M08H) |
| Preparation | This antibody was obtained from a rabbit immunized with purified, recombinant Mouse CD14 (rM CD14; Catalog#50023-M08H; NP_033971.1; Met1-Pro345). |
| Source | Monoclonal Rabbit IgG Clone #503 |
| Purification | Protein A |
| Formulation | 0.2 μm filtered solution in PBS |
| Conjugate | Unconjugated |
| Form | Liquid |
| Shipping | This antibody is shipped as liquid solution at ambient temperature. Upon receipt, store it immediately at the temperature recommended below. |
| Storage | This antibody can be stored at 2℃-8℃ for one month without detectable loss of activity. Antibody products are stable for twelve months from date of receipt when stored at -20℃ to -80℃. Preservative-Free. Avoid repeated freeze-thaw cycles. |
Synonyms: Anti-Cd14 Antibody
Image / Experimental Information
| Image 1 Description | Immunofluorescence staining of Mouse CD14 in Mouse Spleen cells. Cells were fixed with 4% PFA, blocked with 10% serum, and incubated with rabbit anti-mouse CD14 monoclonal antibody (1:60) at 37℃ 1 hour. Then cells were stained with the Alexa Fluor® 488-conjugated Goat Anti-rabbit IgG secondary antibody (green). Positive staining was localized to cell membrane. |
| Image 1 Alt Text | Mouse CD14 Immunofluorescence(IF) 2815 |
| Image 1 URL | Source image |
| Image 2 Description | Immunofluorescence staining of Mouse CD14 in Mouse Spleen cells. Cells were fixed with 4% PFA, blocked with 10% serum, and incubated with rabbit anti-mouse CD14 monoclonal antibody (1:60) at 37℃ 1 hour. Then cells were stained with the Alexa Fluor® 488-conjugated Goat Anti-rabbit IgG secondary antibody (green). Positive staining was localized to cell membrane. |
| Image 2 Alt Text | Mouse CD14 Flow Cytometry (FC) 4977 |
| Image 2 URL | Source image |
Background Information
| Full Name | CD14 molecule |
| Description | The cluster of differentiation (CD) system is commonly used as cell markers in immunophenotyping. Different kinds of cells in the immune system can be identified through the surface CD molecules associating with the immune function of the cell. There are more than 320 CD unique clusters and subclusters have been identified. Some of the CD molecules serve as receptors or ligands important to the cell through initiating a signal cascade which then alter the behavior of the cell. Some CD proteins do not take part in cell signal process but have other functions such as cell adhesion. Cluster of differentiation 14 (CD14) is a member of the CD system. It takes its name from its inclusion in the CD molecule surface marker proteins. CD14 exists in two forms: a form anchored into the membrane or a soluble form. CD14 was found expressed in macrophages, neutrophil granulocyte and dendritic cells. The major function is to serve as a co-receptor (along with TLR4 and MD-2) for the bacterial lipopolysaccharide (LPS) and other pathogen-associated molecular patterns. |
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