| Catalog No. | Size | Price (USD) |
| 10051-MM19-50 | 50 µL | $147.96 |
| 10051-MM19-100 | 100 µL | $251.64 |
| 10051-MM19-200 | 200 µL | $355.32 |
General Information
| Product name | Anti-CD13 Antibody, Mouse Monoclonal |
| Validated applications | WB (FAQ Protocol), IP (FAQ Protocol) |
| Species reactivity | Reacts with: Human |
| Specificity | Human CD13 |
| Immunogen | Recombinant Human CD13 /ANPEP Protein (Catalog#10051-H08H) |
| Preparation | This antibody was produced from a hybridoma resulting from the fusion of a mouse myeloma with B cells obtained from a mouse immunized with purified, recombinant Human CD13 /ANPEP (rh CD13 /ANPEP; Catalog#10051-H08H; NP_001141.2; Lys69-Lys967,603Met/Ile). The IgG fraction of the cell culture supernatant was purified by Protein A affinity chromatography. |
| Source | Monoclonal Mouse IgG1 Clone #19 |
| Purification | Protein A |
| Formulation | 0.2 μm filtered solution in PBS |
| Conjugate | Unconjugated |
| Form | Liquid |
| Shipping | This antibody is shipped as liquid solution at ambient temperature. Upon receipt, store it immediately at the temperature recommended below. |
| Storage | This antibody can be stored at 2℃-8℃ for one month without detectable loss of activity. Antibody products are stable for twelve months from date of receipt when stored at -20℃ to -80℃. Preservative-Free. Avoid repeated freeze-thaw cycles. |
Synonyms: Anti-AP-M Antibody; Anti-AP-N Antibody; Anti-APN Antibody; Anti-CD13 Antibody; Anti-GP150 Antibody; Anti-hAPN Antibody; Anti-LAP1 Antibody; Anti-P150 Antibody; Anti-PEPN Antibody
Image / Experimental Information
| Image 1 Description | Anti-ANPEP mouse monoclonal antibody at 1:500 dilution Lane A: Jurkat Whole Cell Lysate Lane B: HepG2 Whole Cell Lysate Lysates/proteins at 30 μg per lane. Secondary Goat Anti-Mouse IgG (H+L)/HRP at 1/10000 dilution. Developed using the ECL technique. Performed under reducing conditions. Predicted band size:110 kDa Observed band size:140 kDa |
| Image 1 Alt Text | Human CD13 Western blot (WB) 31583 |
| Image 1 URL | Source image |
| Image 2 Description | Anti-ANPEP mouse monoclonal antibody at 1:500 dilution Lane A: Jurkat Whole Cell Lysate Lane B: HepG2 Whole Cell Lysate Lysates/proteins at 30 μg per lane. Secondary Goat Anti-Mouse IgG (H+L)/HRP at 1/10000 dilution. Developed using the ECL technique. Performed under reducing conditions. Predicted band size:110 kDa Observed band size:140 kDa |
| Image 2 Alt Text | Human CD13 Immunoprecipitation(IP) 31584 |
| Image 2 URL | Source image |
Background Information
| Full Name | alanyl (membrane) aminopeptidase |
| Description | Aminopeptidase N (ANPEP or APN), also known as CD13, is a cell-surface metalloprotease located in the small-intestinal and renal microvillar membrane, as well as other plasma membranes. It belongs to the peptidase M1 family. CD13 plays a role in the final digestion of peptides generated from hydrolysis of proteins by gastric and pancreatic proteases and is involved in the metabolism of regulatory peptides by diverse cell types. CD13/APN is a potent regulator of angiogenesis which is essential for tumor invasion and metastasis, and its transcription in activated endothelial cells is induced by angiogenic growth factors via the RAS/MAPK pathway. In addition, this enzyme has been shown to participate in antigen processing and presentation, and accordingly, defects in this gene appear to be a cause of various types of leukemia or lymphoma and carcinomas. |
| References |
|
title: Bat genomes illuminate adaptations to viral tolerance and disease resistance
authors: Ariadna E. Morales; Yue Dong; ...; Michael Hiller
journal: Nature
date: 2025-01-29
pmid: 39880942
doi: 10.1038/s41586-024-08471-0
pmcid: 11821529
cited_by_count: 38
techniques: Cell Culture; Conjugation Assay; Construct; Control; Expressing; Infection; Plasmid Preparation; Stable Transfection; Staining; Transfection; Two Tailed Test; Western Blot
bioz_score: 93
