| Catalog No. | Size | Price (USD) |
| 50722-T48-50 | 50 µL | $147.96 |
| 50722-T48-100 | 100 µL | $251.64 |
| 50722-T48-200 | 200 µL | $355.32 |
General Information
| Product name | Anti-CD53 Antibody, Rabbit Polyclonal |
| Validated applications | WB (FAQ Protocol), ELISA (FAQ Protocol) |
| Species reactivity | Reacts with: Mouse |
| Specificity | Mouse CD53 |
| Immunogen | Recombinant Mouse CD53 Protein (Catalog#50722-M07H) |
| Preparation | Produced in rabbits immunized with purified, recombinant Mouse CD53 (rM CD53; Catalog#50722-M07H; Q61451; Glu107-Asn181). CD53 specific IgG was purified by Mouse CD53 affinity chromatography. |
| Source | Polyclonal Rabbit IgG |
| Purification | Protein A & Antigen Affinity |
| Formulation | 0.2 μm filtered solution in PBS |
| Conjugate | Unconjugated |
| Form | Liquid |
| Shipping | This antibody is shipped as liquid solution at ambient temperature. Upon receipt, store it immediately at the temperature recommended below. |
| Storage | This antibody can be stored at 2℃-8℃ for one month without detectable loss of activity. Antibody products are stable for twelve months from date of receipt when stored at -20℃ to -80℃. Preservative-Free. Avoid repeated freeze-thaw cycles. |
Synonyms: Anti-Cd53 Antibody; Anti-Ox-44 Antibody; Anti-Tspan25 Antibody
Image / Experimental Information
| Image 1 Description | Anti-CD53 rabbit polyclonal antibody at 1:500 dilution Lane A: Mouse Brain tissue lysate Lysates/proteins at 30 μg per lane. Secondary Goat Anti-Rabbit IgG (H+L)/HRP at 1/10000 dilution. Developed using the ECL technique. Performed under reducing conditions. Predicted band size:24 kDa Observed band size:24 kDa |
| Image 1 Alt Text | Mouse CD53 Western blot (WB) 20110 |
| Image 1 URL | Source image |
Background Information
| Full Name | CD53 molecule |
| Description | CD53 is a member of the transmembrane 4 superfamily, also called the tetraspanin family. Most of these members are cell-surface proteins that are characterized by the presence of four hydrophobic domains. These proteins mediate signal transduction events that play a role in the regulation of cell development, activation, growth and motility. CD53 is a cell surface glycoprotein that is known to complex with integrins. Familial deficiency of CD53 gene has been linked to an immunodeficiency associated with recurrent infectious diseases caused by bacteria, fungi and viruses. CD53 contributes to the transduction of CD2-generated signals in T cells and natural killer cells and has been suggested to play a role in growth regulation. |
| References |
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