| Catalog No. | Size | Price (USD) |
| 102006-T40-50 | 50 µL | $147.96 |
| 102006-T40-100 | 100 µL | $251.64 |
| 102006-T40-200 | 200 µL | $355.32 |
General Information
| Product name | Anti-CD13 Antibody, Rabbit Polyclonal |
| Validated applications | WB (FAQ Protocol), IHC-P (FAQ Protocol) |
| Species reactivity | Reacts with: Rat |
| Specificity | Rat Mouse (Species predicted to react based on 100% sequence homology) |
| Immunogen | A synthetic peptide corresponding to the N-terminus of the Rat CD13 |
| Preparation | Produced in rabbits immunized with a synthetic peptide corresponding to the N-terminus of the Rat CD13, and purified by antigen affinity chromatography. |
| Source | Polyclonal Rabbit IgG |
| Purification | Protein A & Antigen Affinity |
| Formulation | 0.2 μm filtered solution in PBS |
| Conjugate | Unconjugated |
| Form | Liquid |
| Shipping | This antibody is shipped as liquid solution at ambient temperature. Upon receipt, store it immediately at the temperature recommended below. |
| Storage | This antibody can be stored at 2℃-8℃ for one month without detectable loss of activity. Antibody products are stable for twelve months from date of receipt when stored at -20℃ to -80℃. Preservative-Free. Avoid repeated freeze-thaw cycles. |
Synonyms: Anti-Anpep Antibody; Anti-AP-M Antibody; Anti-AP-N Antibody; Anti-Apm Antibody; Anti-Apn Antibody; Anti-KZP Antibody; Anti-Lap1 Antibody; Anti-rAPN Antibody
Image / Experimental Information
| Image 1 Description | Anti-CD13 rabbit polyclonal antibody at 1:500 dilution Lane A:THP1 Whole Cell Lysate Lane B: U937 Whole Cell Lysate Lysates/proteins at 30 μg per lane. Secondary Goat Anti-Rabbit IgG (H+L)/HRP at 1/10000 dilution. Developed using the ECL technique. Performed under reducing conditions. Predicted band size:110 kDa Observed band size:140 kDa |
| Image 1 Alt Text | Rat CD13 Western blot (WB) 35097 |
| Image 1 URL | Source image |
| Image 2 Description | Anti-CD13 rabbit polyclonal antibody at 1:500 dilution Lane A:THP1 Whole Cell Lysate Lane B: U937 Whole Cell Lysate Lysates/proteins at 30 μg per lane. Secondary Goat Anti-Rabbit IgG (H+L)/HRP at 1/10000 dilution. Developed using the ECL technique. Performed under reducing conditions. Predicted band size:110 kDa Observed band size:140 kDa |
| Image 2 Alt Text | Rat CD13 Immunohistochemistry(IHC) 35098 |
| Image 2 URL | Source image |
| Image 3 Description | Anti-CD13 rabbit polyclonal antibody at 1:500 dilution Lane A:THP1 Whole Cell Lysate Lane B: U937 Whole Cell Lysate Lysates/proteins at 30 μg per lane. Secondary Goat Anti-Rabbit IgG (H+L)/HRP at 1/10000 dilution. Developed using the ECL technique. Performed under reducing conditions. Predicted band size:110 kDa Observed band size:140 kDa |
| Image 3 Alt Text | Rat CD13 Immunohistochemistry(IHC) 35099 |
| Image 3 URL | Source image |
| Image 4 Description | Anti-CD13 rabbit polyclonal antibody at 1:500 dilution Lane A:THP1 Whole Cell Lysate Lane B: U937 Whole Cell Lysate Lysates/proteins at 30 μg per lane. Secondary Goat Anti-Rabbit IgG (H+L)/HRP at 1/10000 dilution. Developed using the ECL technique. Performed under reducing conditions. Predicted band size:110 kDa Observed band size:140 kDa |
| Image 4 Alt Text | Rat CD13 Immunohistochemistry(IHC) 35100 |
| Image 4 URL | Source image |
| Image 5 Description | Anti-CD13 rabbit polyclonal antibody at 1:500 dilution Lane A:THP1 Whole Cell Lysate Lane B: U937 Whole Cell Lysate Lysates/proteins at 30 μg per lane. Secondary Goat Anti-Rabbit IgG (H+L)/HRP at 1/10000 dilution. Developed using the ECL technique. Performed under reducing conditions. Predicted band size:110 kDa Observed band size:140 kDa |
| Image 5 Alt Text | Rat CD13 Immunohistochemistry(IHC) 35101 |
| Image 5 URL | Source image |
Background Information
| Full Name | alanyl (membrane) aminopeptidase |
| Description | Aminopeptidase N (ANPEP or APN), also known as CD13, is a cell-surface metalloprotease located in the small-intestinal and renal microvillar membrane, as well as other plasma membranes. It belongs to the peptidase M1 family. CD13 plays a role in the final digestion of peptides generated from hydrolysis of proteins by gastric and pancreatic proteases and is involved in the metabolism of regulatory peptides by diverse cell types. CD13/APN is a potent regulator of angiogenesis which is essential for tumor invasion and metastasis, and its transcription in activated endothelial cells is induced by angiogenic growth factors via the RAS/MAPK pathway. In addition, this enzyme has been shown to participate in antigen processing and presentation, and accordingly, defects in this gene appear to be a cause of various types of leukemia or lymphoma and carcinomas. |
| References |
|
title: Proteomic profile of human dental follicle stem cells and apical papilla stem cells.
authors: Tong Lei; Xiaoshuang Zhang; ...; Hongwu Du
journal: Journal of proteomics
date: 2021-06-18
pmid: 32800794
doi: 10.1016/j.jprot.2020.103928
cited_by_count: 18
techniques: Incubation; Western Blot
bioz_score: 90
-HD14DE0105-WB.png){kind=link}
-HD14DE0105-1000-rat-kidney-IHC-P.png){kind=link}
-HD14DE0105-1000-rat-small-intestine-IHC-P.png){kind=link}
-HD14DE0105-1000-mouse-kidney-IHC-P.png){kind=link}
-HD14DE0105-1000-mouse-small-intestine-IHC-P.png){kind=link}