Recombinant Anti-CD5L Antibody, Rabbit Monoclonal sinobiological 50020-R038

$171.00
In stock
SKU
50020-R038
Catalog No.SizePrice (USD)
50020-R038-5050 µL$177.58
50020-R038-100100 µL$340.51

General Information

Product nameRecombinant Anti-CD5L Antibody, Rabbit Monoclonal
Validated applicationsELISA (FAQ Protocol)
Species reactivityReacts with: Mouse
SpecificityMouse CD5L
ImmunogenRecombinant Mouse CD5L protein (Catalog#50020-M08H)
PreparationThis antibody was obtained from a rabbit immunized with purified, recombinant Mouse CD5L / Aim (rM CD5L; Catalog#50020-M08H; Met 1-Val 352; NP_033820.2) .
SourceMonoclonal Rabbit IgG Clone #38
PurificationProtein A
Formulation0.2 μm filtered solution in PBS
ConjugateUnconjugated
FormLiquid
ShippingThis antibody is shipped as liquid solution at ambient temperature. Upon receipt, store it immediately at the temperature recommended below.
StorageThis antibody can be stored at 2℃-8℃ for one month without detectable loss of activity. Antibody products are stable for twelve months from date of receipt when stored at -20℃ to -80℃. Preservative-Free. Avoid repeated freeze-thaw cycles.

Synonyms: Anti-1/6 Antibody; Anti-AAC-11 Antibody; Anti-AIM Antibody; Anti-Api6 Antibody; Anti-Cd5l Antibody; Anti-CT2 Antibody; Anti-mAIM Antibody; Anti-Pdp Antibody; Anti-Sp-alpha Antibody

Background Information

Full NameCD5 molecule-like
DescriptionCD5L, also known as CD5 antigen-like, is a soluble protein belonging to group B of the scavenger receptor cysteine-rich (SRCR) superfamily and contains three SRCR domains. It is a secreted glycoprotein and expressed by macrophages presentin lymphoid tissues (spleen, lymph node, thymus, and bone marrow). It binds to myelomonocytic and lymphoid cells and may play an important role in the regulation of the innate and adaptive immune systems. CD5L functions as a pattern recognition molecule by binding both lipoteichoic acid (LTA) on Gram positive and lipopolysaccharide (LPS) on Gram negative bacteria. and the SRCR domain 1 of CD5L retains both the LPS and LTA binding activities. In addtion, it is revealed that CD5L seems to play a role as an inhibitor of apoptosis.
References
  1. Resnick, D. et al., 1994, Trends Biochem. Sci. 19: 5-8.
  2. Gebe, J. A. et al., 1997, J. Biol. Chem. 272 (10): 6151–6158.
  3. Sarrias, M.R. et al., 2004, Crit. Rev. Immunol. 24: 1-37.
  4. Mukhopadhyay, S. and Gordon, S., 2004, Immunobiology 209: 39-49.
  5. Sarrias, M. R. et al.,2005, J. Biol. Chem. 280 (42): 35391–35398.

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