Recombinant Anti-Ephrin B3 Antibody, Rabbit Monoclonal sinobiological 51147-R019

$171.00
In stock
SKU
51147-R019
Catalog No.SizePrice (USD)
51147-R019-5050 µL$177.58
51147-R019-100100 µL$340.51

General Information

Product nameRecombinant Anti-Ephrin B3 Antibody, Rabbit Monoclonal
Validated applicationsELISA (FAQ Protocol)
Species reactivityReacts with: Mouse
SpecificityMouse Ephrin B3
ImmunogenRecombinant Mouse Ephrin B3 / EFNB3 Protein (Catalog#51147-M08H)
PreparationThis antibody was obtained from a rabbit immunized with purified, recombinant Mouse Ephrin B3 / EFNB3 (rM Ephrin B3 / EFNB3; Catalog#51147-M08H; NP_031937.1; Met1-Ala227).
SourceMonoclonal Rabbit IgG Clone #019
PurificationProtein A
Formulation0.2 μm filtered solution in PBS
ConjugateUnconjugated
FormLiquid
ShippingThis antibody is shipped as liquid solution at ambient temperature. Upon receipt, store it immediately at the temperature recommended below.
StorageThis antibody can be stored at 2℃-8℃ for one month without detectable loss of activity. Antibody products are stable for twelve months from date of receipt when stored at -20℃ to -80℃. Preservative-Free. Avoid repeated freeze-thaw cycles.

Synonyms: Anti-EFL-6 Antibody; Anti-Efnb3 Antibody; Anti-ELF-3 Antibody; Anti-Elk-L3 Antibody; Anti-Epl8 Antibody; Anti-LERK-8 Antibody; Anti-NLERK-2 Antibody

Background Information

Full Nameephrin-B3
DescriptionEphrin B3 belongs to the ephrin family. Ephrins are divided into the ephrin-A (EFNA) class, which are anchored to the membrane by a glycosylphosphatidylinositol linkage, and the ephrin-B (EFNB) class, which are transmembrane proteins. Ephrin B3 is important in brain development as well as in its maintenance. It is especially important for forebrain function since its expression levels were particularly high in several forebrain subregions compared to other brain subregions. Ephrin B3 binds to, and induce the collapse of, commissural axons/growth cones in vitro. It may play a role in constraining the orientation of longitudinally projecting axons.
References
  1. Takemoto M, et al. (2002) Ephrin-B3-EphA4 interactions regulate the growth of specific thalamocortical axon populations in vitro. Eur J Neurosci. 16(6):1168-72.
  2. Brckner K, et al. (1999) EphrinB ligands recruit GRIP family PDZ adaptor proteins into raft membrane microdomains. Neuron. 22(3):511-24.
  3. Bergemann A, et al. (1998) Ephrin-B3, a ligand for the receptor EphB3, expressed at the midline of the developing neural tube. Oncogene. 16(4):471-80.

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