| Catalog No. | Size | Price (USD) |
| 50310-R015-50 | 50 µL | $177.58 |
| 50310-R015-100 | 100 µL | $340.51 |
General Information
| Product name | Recombinant Anti-kynureninase/KYNU Antibody, Rabbit Monoclonal |
| Validated applications | ELISA (FAQ Protocol) |
| Species reactivity | Reacts with: Mouse |
| Specificity | Mouse kynureninase/KYNU Has cross-reactivity in ELISA with Human KYNU |
| Immunogen | Recombinant Mouse KYNU protein (Catalog#50310-M08B) |
| Preparation | This antibody was obtained from a rabbit immunized with purified, recombinant Mouse KYNU (Catalog#50310-M08B; Q9CXF0; Met1-Ser464). |
| Source | Monoclonal Rabbit IgG Clone #015 |
| Purification | Protein A |
| Formulation | 0.2 μm filtered solution in PBS |
| Conjugate | Unconjugated |
| Form | Liquid |
| Shipping | This antibody is shipped as liquid solution at ambient temperature. Upon receipt, store it immediately at the temperature recommended below. |
| Storage | This antibody can be stored at 2℃-8℃ for one month without detectable loss of activity. Antibody products are stable for twelve months from date of receipt when stored at -20℃ to -80℃. Preservative-Free. Avoid repeated freeze-thaw cycles. |
Synonyms: Anti-4432411A05Rik Antibody; Anti-Kynu Antibody
Background Information
| Full Name | kynureninase |
| Description | KYNU (Kynureninase) is a Protein Coding gene. KYNU is a pyridoxal-5'-phosphate (pyridoxal-P) dependent enzyme that catalyzes the cleavage of L-kynurenine and L-3-hydroxykynurenine into anthranilic and 3-hydroxyanthranilic acids, respectively. Genetic studies in the mouse and the human suggest that kynureninase activity may influence blood pressure and renal function. The gene coding kynureninase (KYNU) is also located on chromosome band 2q14-q23, where a linkage peak for essential hypertension was previously detected in the Chinese Han population. The results show that the rare KYNU variant Arg188Gln affects kynureninase activity and are consistent with the hypothesis that this mutation can predispose to essential hypertension. Diseases associated with KYNU include Hydroxykynureninuria and Vertebral, Cardiac, Renal, And Limb Defects Syndrome 2. |
| References |
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