| Catalog No. | Size | Price (USD) |
| 68139-H001-5 | 5 mg | $740.55 |
| 68139-H001-25 | 25 mg | $2,221.66 |
| 68139-H001-500 | 500 µg | $222.17 |
General Information
| Product name | Anti-CD3 (Research Grade Teplizumab Biosimilar) |
| Species reactivity | Reacts with: Human |
| Specificity | CD3 |
| Preparation | This product is a recombinant monoclonal antibody expressed from HEK293 cells. |
| Source | IgG1, Kappa |
| Purification | Protein A |
| Formulation | Histidine and Arginine buffer containing 120mM NaCl, 0.02% Tween 80, pH6.0 |
| Conjugate | Unconjugated |
| Endotoxin | ≦ 1 EU/mg |
| Form | Liquid |
| Shipping | This antibody is shipped as liquid solution at ambient temperature. Upon receipt, store it immediately at the temperature recommended below. |
| Storage | Antibody products are stable for twelve months from date of receipt when stored at -20℃ to -80℃. Preservative-Free. Avoid repeated freeze-thaw cycles. |
Image / Experimental Information
| Image 1 Description | ≥95 % as determined by SDS-PAGE. |
| Image 1 Alt Text | Human CD3-Teplizumab Enzyme linked immunosorbent assay (ELISA) 46051 |
| Image 1 URL | Source image |
| Image 2 Description | ≥95 % as determined by SDS-PAGE. |
| Image 2 Alt Text | Human CD3-Teplizumab Enzyme linked immunosorbent assay (ELISA) 46052 |
| Image 2 URL | Source image |
title: Butyrophilin 2A2 promotes T cell immunoregulation via CD45 phosphatase activation and protects against murine autoimmune glomerulonephritis and pregnancy loss.
authors: Shafat Ali; Anders H Berg; ...; S Ananth Karumanchi
journal: Nature Communications
date: 2026-01-08
pmid: 41507164
cited_by_count: 0
techniques: Activation Assay; Derivative Assay; In Vitro; Recombinant
bioz_score: 94
title: Targeting SHP2 to reverse immune evasion and resistance to anti-PD-1 therapy in non-small cell lung cancer
authors: Shiwei Chen; Dingguo Wang; ...; Yongbing Wu
journal: Cell Communication and Signaling : CCS
date: 2025-11-06
pmid: 41199296
cited_by_count: 0
techniques: Cell Isolation; Enzyme-linked Immunosorbent Assay; Incubation; Isolation; Purification
bioz_score: 94
title: Age-associated immune dysregulation and B cell dysfunction drive severe outcomes in SFTSV infection
authors: Eun-Ha Kim; Ho Bin Jang; ...; Alison M. Kell
journal: PLoS Pathogens
date: 2025-08-12
pmid: 40794649
doi: 10.1371/journal.ppat.1013402
cited_by_count: 0
techniques: Blocking Assay; Expressing; Gene Expression; Immunohistochemistry; Incubation; Infection; MANN-WHITNEY; Multiplex Assay; Polymer; Staining; Two Tailed Test
bioz_score: 94
title: Engaging PD-1 rescues regulatory T cell function and inhibits inflammatory T cells in rheumatoid arthritis.
authors: Kaustav Chowdhury; Uma Kumar; ...; Dipendra Kumar Mitra
journal: Clinical and experimental immunology
date: 2025-05-28
pmid: 40434878
doi: 10.1093/cei/uxaf035
cited_by_count: 0
techniques: Blocking Assay; Cell Culture; Isolation; Saline
bioz_score: 94
title: A Multispecific Checkpoint Inhibitor Nanofitin with a Fast Tumor Accumulation Property and Anti-Tumor Activity in Immune Competent Mice.
authors: Perrine Jacquot; Javier Muñoz-Garcia; ...; Dominique Heymann
journal: Biomolecules
date: 2025-04-30
pmid: 40305184
cited_by_count: 0
techniques: Activity Assay; Binding Assay; Cell Analysis; Cell Culture; Control; Drug discovery; Expressing; Flow Cytometry; Injection; Labeling; Produced; Software; Staining
bioz_score: 94
title: Monovalent Anti-CD3 Antibodies Effectively Eliminate the TCR-Positive Fraction of TCR-Deleted Allogeneic CAR-T Cells to Prevent GVHD.
authors: Ji Hwan Kim; Hyori Kim; ...; Kyungho Choi
journal: Immune Network
date: 2024-12-01
pmid: 39801735
doi: 10.4110/in.2024.24.e43
cited_by_count: 0
bioz_score: 94
title: Antigen-specific B cells direct T follicular- like helper cells into lymphoid follicles to mediate Mycobacterium tuberculosis control
authors: Rosemary V. Swanson; Ananya Gupta; ...; Shabaana A. Khader
journal: Nature immunology
date: 2024-05-29
pmid: 37012543
pmcid: 11133959
cited_by_count: 46
techniques: Control; Expressing; Light Microscopy; Software; Staining
bioz_score: 94
title: Identifying transcriptomic profiles of iron-quercetin complex treated peripheral blood mononuclear cells from healthy volunteers and diabetic patients.
authors: Phattarawadee Innuan; Chonticha Sirikul; ...; Jiraporn Kantapan
journal: Scientific Reports
date: 2024-04-24
pmid: 38658734
doi: 10.1038/s41598-024-60197-1
cited_by_count: 1
techniques: Flow Cytometry; Fluorescence; Incubation; Recombinase Polymerase Amplification; Software; Suspension
bioz_score: 94
title: Multi-omics joint analysis revealed the metabolic profile of retroperitoneal liposarcoma.
authors: Fu'an Xie; Yujia Niu; ...; Wengang Li
journal: Frontiers of medicine
date: 2023-12-29
pmid: 38157196
doi: 10.1007/s11684-023-1020-z
cited_by_count: 11
techniques: CCK-8 Assay; Cell Culture; Incubation; Viability Assay
bioz_score: 94
title: Highly proliferative and hypodifferentiated CAR-T cells targeting B7-H3 enhance antitumor activity against ovarian and triple-negative breast cancers.
authors: Xiaoshuai Zhang; Haiyan Guo; ...; Jianwei Zhu
journal: Cancer letters
date: 2023-09-06
pmid: 37597651
doi: 10.1016/j.canlet.2023.216355
cited_by_count: 18
techniques: Activation Assay; Control; Staining
bioz_score: 94
title: NAV-003, a bispecific antibody targeting a unique mesothelin epitope and CD3ε with improved cytotoxicity against humoral immunosuppressed tumors.
authors: Luigi Grasso; Qun Jiang; ...; J Bradford Kline
journal: European Journal of Immunology
date: 2023-08-14
pmid: 37146241
doi: 10.1002/eji.202250309
cited_by_count: 4
techniques: Binding Assay; Enzyme-linked Immunosorbent Assay; Immunofluorescence; Recombinant; Staining
bioz_score: 94
title: Engineering of a Bispecific Nanofitin with Immune Checkpoint Inhibitory Activity Conditioned by the Cross-Arm Binding to EGFR and PDL1.
authors: Perrine Jacquot; Javier Muñoz-Garcia; ...; Dominique Heymann
journal: Biomolecules
date: 2023-05-17
pmid: 37189383
cited_by_count: 3
techniques: Activity Assay; Concentration Assay; Incubation; Produced
bioz_score: 94
title: GMP development and preclinical validation of CAR-T cells targeting a lytic EBV antigen for therapy of EBV-associated malignancies.
authors: Xi Zhang; Tiaoxia Wang; ...; Renata Stripecke
journal: Frontiers in Immunology
date: 2023-03-01
pmid: 36817460
doi: 10.3389/fimmu.2023.1103695
cited_by_count: 15
techniques: Activity Assay; Incubation; Real-time Polymerase Chain Reaction; Staining
bioz_score: 94
title: DNA-Templated Anchoring of Proteins for Programmable Cell Functionalization and Immunological Response.
authors: Mengyi Xiong; Gezhi Kong; ...; Weihong Tan
journal: Nano Letters
date: 2023-01-12
pmid: 36577045
cited_by_count: 4
techniques: Bicinchoninic Acid Protein Assay; Labeling; Plasmid Preparation
bioz_score: 94
title: NAMPT is a metabolic checkpoint of IFNγ-producing CD4 + T cells in lupus nephritis.
authors: Mengyuan Li; Yimei Lai; ...; Hui Zhang
journal: Molecular therapy : the journal of the American Society of Gene Therapy
date: 2023-01-09
pmid: 36146932
doi: 10.1016/j.ymthe.2022.09.013
cited_by_count: 23
techniques: Cell Culture; Flow Cytometry; In Vitro; Purification; Recombinant
bioz_score: 94
title: A homodimeric IL-15 superagonist F4RLI with easy preparation, improved half-life, and potent antitumor activities.
authors: Liangyin Lv; Hui Wang; ...; Huili Lu
journal: Applied microbiology and biotechnology
date: 2022-10-27
pmid: 36184689
doi: 10.1007/s00253-022-12209-1
cited_by_count: 3
techniques: Proliferation Assay; Software; Staining
bioz_score: 94
title: Self-Assembly of a Multifunction DNA Tetrahedron for Effective Delivery of Aptamer PL1 and Pcsk9 siRNA Potentiate Immune Checkpoint Therapy for Colorectal Cancer.
authors: Wenjing Guo; Huabin Gao; ...; Anjia Han
journal: ACS Applied Materials & Interfaces
date: 2022-07-22
pmid: 35817627
cited_by_count: 20
techniques: Cell Culture; Enzyme-linked Immunosorbent Assay; Incubation; Proliferation Assay; Recombinant
bioz_score: 94
title: lncRNA STAT4-AS1 Inhibited TH17 Cell Differentiation by Targeting ROR γ t Protein
authors: Hanlin He; Xiangjie Qiu; ...; Yurong Tan
journal: Journal of immunology research
date: 2022-04-28
doi: 10.1155/2022/8307280
pmcid: 9071868
cited_by_count: 5
techniques: Cell Differentiation
bioz_score: 90
title: Intratumoral delivery of a novel oncolytic adenovirus encoding human antibody against PD-1 elicits enhanced antitumor efficacy
authors: Ping Zhou; Xuchen Wang; ...; Dongming Zhou
journal: Molecular therapy oncolytics
date: 2022-04-25
pmid: 35615266
doi: 10.1016/j.omto.2022.04.007
pmcid: 9118129
cited_by_count: 9
techniques: Enzyme-linked Immunosorbent Assay; Functional Assay; Knock-In
bioz_score: 94
title: Characterization of a novel bispecific antibody targeting tissue factor-positive tumors with T cell engagement
authors: Zhidi Pan; Jie Chen; ...; Jianwei Zhu
journal: Acta Pharmaceutica Sinica. B
date: 2021-11-03
doi: 10.1016/j.apsb.2021.10.028
pmcid: 9279644
cited_by_count: 17
techniques: Activation Assay; Binding Assay; Expressing; FACS; Flow Cytometry; Fluorescence; High Performance Liquid Chromatography; Immunohistochemistry; In Vitro; Incubation; Inhibition; Labeling; Liquid Chromatography; Lysis; Mass Spectrometry; Molecular Weight; Purification; SDS Page; Staining; Two Tailed Test
bioz_score: 94
title: Exosomes derived from LPS-stimulated human thymic mesenchymal stromal cells enhance inflammation via thrombospondin-1
authors: Qianru Li; Jing Li; ...; Ying Du
journal: Bioscience Reports
date: 2021-10-01
doi: 10.1042/bsr20203573
cited_by_count: 0
techniques: Cell Isolation; Flow Cytometry; Isolation; Western Blot
bioz_score: 94
title: Semaphorin 3A contributes to sepsis-induced immunosuppression by impairing CD4 + T cell anergy
authors: Yulei Gao; Chunxue Wang; ...; Yanfen Chai
journal: Molecular medicine reports
date: 2021-04-01
pmid: 33649856
doi: 10.3892/mmr.2021.11941
pmcid: 7930987
cited_by_count: 7
techniques: Activation Assay; Activity Assay; Expressing; In Vitro; Recombinant
bioz_score: 94
title: Anti-PD-L1 DNA aptamer antagonizes the interaction of PD-1/PD-L1 with antitumor effect.
authors: Tian Gao; Zheng Mao; ...; Renjun Pei
journal: Journal of Materials Chemistry B
date: 2021-03-25
pmid: 33319876
doi: 10.1039/d0tb01668c
cited_by_count: 16
techniques: Activation Assay; Cell Culture; Centrifugation; Clinical Proteomics; Concentration Assay; Enzyme-linked Immunosorbent Assay; FACS; Flow Cytometry; Incubation; Isolation; Negative Control; Quantitation Assay
bioz_score: 94
title: Characterization of the Therapeutic Effects of Novel Chimeric Antigen Receptor T Cells Targeting CD38 on Multiple Myeloma.
authors: Xiaorui Li; Yaru Feng; ...; Jianxun Wang
journal: Frontiers in Oncology
date: 2021-01-01
pmid: 34513682
cited_by_count: 4
techniques: Activation Assay; Cell Culture; Flow Cytometry; Isolation; Transduction
bioz_score: 94
title: PD-1+ Tim3+ tumor-infiltrating CD8 T cells sustain the potential for IFN-γ production, but lose cytotoxic activity in ovarian cancer.
authors: Masaaki Sawada; Kumiko Goto; ...; Hisashi Wada
journal: International immunology
date: 2021-01-01
pmid: 32009163
doi: 10.1093/intimm/dxaa010
cited_by_count: 30
techniques: Clone Assay; Cloning; Expressing; Flow Cytometry; Labeling; Membrane; Plasmid Preparation; Recombinant; Staining; Transfection
bioz_score: 94
title: PD-1 Blockade Reinvigorates Bone Marrow CD8+ T Cells from Patients with Multiple Myeloma in the Presence of TGFβ Inhibitors
authors: Minsuk Kwon; Chang Gon Kim; ...; Eui-Cheol Shin
journal: Clinical Cancer Research
date: 2020-01-15
doi: 10.1158/1078-0432.ccr-19-0267
cited_by_count: 24
techniques: Amplification; DNA Extraction; Expressing; In Vitro; Incubation; Isolation; Mutagenesis; Purification; Sequencing; Staining
bioz_score: 94
title: A stromal cell population that inhibits adipogenesis in mammalian fat depots.
authors: Petra C Schwalie; Hua Dong; ...; Bart Deplancke
journal: Nature
date: 2018-12-11
pmid: 29925944
doi: 10.1038/s41586-018-0226-8
cited_by_count: 325
techniques: Generated; Incubation
bioz_score: 94
title: Optimized Expression and Characterization of a Novel Fully Human Bispecific Single-Chain Diabody Targeting Vascular Endothelial Growth Factor165 and Programmed Death-1 in Pichia pastoris and Evaluation of Antitumor Activity In Vivo
authors: Chenghao Xiong; Yingqing Mao; ...; Yu Liu
journal: International Journal of Molecular Sciences
date: 2018-09-25
pmid: 30257416
doi: 10.3390/ijms19102900
pmcid: 6213929
cited_by_count: 14
techniques: Activation Assay; CCK-8 Assay; Enzyme-linked Immunosorbent Assay; Gradient Centrifugation; Incubation; Isolation; Magnetic Cell Separation; Proliferation Assay; Purification; Two Tailed Test
bioz_score: 94
title: Modified J-chain
authors: Bruce Keyt; Leonard George Presta; ...; Ramesh Baliga
date: 2018-04-24
cited_by_count: 0
techniques: Construct; Expressing; Modification; Molecular Weight; Purification; Transfection
bioz_score: 94
title: Anti-CD324 monoclonal antibodies and uses thereof
authors: Robert A. Stull; Monette Aujay; ...; David Liu
date: 2017-01-03
cited_by_count: 0
techniques: Adjuvant; Enzyme-linked Immunosorbent Assay; Produced; Recombinant
bioz_score: 94
title: Tumor-Infiltrating Immune Cells Are Associated With Prognosis of Gastric Cancer
authors: Kai Liu; Kun Yang; ...; JianKun Hu
journal: Medicine
date: 2015-09-01
doi: 10.1097/md.0000000000001631
cited_by_count: 78
techniques: Activity Assay; Blocking Assay; Immunohistochemistry; Incubation; Polymer
bioz_score: 94
title: Transcriptional Profiling Reveals Crosstalk Between Mesenchymal Stem Cells and Endothelial Cells Promoting Prevascularization by Reciprocal Mechanisms
authors: Junxiang Li; Ying Ma; ...; Qiong Wu
journal: Stem cells and development
date: 2015-03-01
pmid: 25299975
doi: 10.1089/scd.2014.0330
pmcid: 4333618
cited_by_count: 16
techniques: FACS; Incubation; Isolation; Microscopy; Protein Extraction; RNA Extraction
bioz_score: 94
title: Heat Shock Cognate 70 Regulates the Translocation and Angiogenic Function of Nucleolin
authors: Yanping Ding; Nan Song; ...; Yongzhang Luo
journal: Arteriosclerosis, thrombosis, and vascular biology
date: 2012-09-01
doi: 10.1161/atvbaha.112.247502
cited_by_count: 30
bioz_score: 94
