Anti-SN38 Mouse mAb _ 31905ES yeasen
$395.00
In stock
SKU
31905ES60
Product Description
SN38 is the active metabolite of the chemotherapy drug irinotecan (Camptosar). It is a topoisomerase I inhibitor, prevents the enzyme from properly resealing the DNA strands after they have been unwound, which leads to the accumulation of DNA damage.
Specifications
| Source | Monoclonal anti-SN38 antibody, is produced from a hybridoma which was obtained from a mouse immunized with SN38. |
| Host | Mouse |
| Purity | ＞ 95% as determined by reduced SDS-PAGE ＞ 99% as determined by non-reduced SDS-PAGE > 99% as determined by SEC-HPLC |
| Concentration | 1 mg/mL |
| Buffer | 1×PBS, pH7.4. Type Monoclonal Antibody |
| Cat.No. | 31905ES60/31905ES80 |
| Size | 100 μg/1 mg |
| Isotype | IgG 1 |
| Activity | EC 50 =80.5 ng/mL by ELISA |
Applications
- ELISA
Storage
This product should be stored at -25~-15℃ for one year, do not freeze.
Notes
This product is for research use only. Please operate with lab coats and disposable gloves, for your safety. Data SDS-PAGE Anti-SN-38 mouse mAb on SDS-PAGE under reduced condition. The purity is 95.5% Anti-SN-38 mouse mAb on SDS-PAGE under non-reduced condition. The purity is 99.2%. S EC-HPLC The purity of Anti-SN-38 mouse mAb is 100% as determined by SEC-HPLC. ELISA Data Dose response curve shows that the EC 50 of Anti-SN-38 mouse mAb is 80.5 n g/mL.
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