Human IGF2R Protein, His-Avi Tag yeasen
$175.00
In stock
SKU
93779ES25
Product Description
IGF-II R is a type I transmembrane glycoprotein that contains a 2,264 aa extracellular region, a 23 aa transmembrane segment segment and a 164 aa cytoplasmic tail. The extracellular region consists of 15 contiguous "binding" repeats of about 150 aa each. This receptor has various functions, including in the intracellular trafficking of lysosomal enzymes, the activation of transforming growth factor beta, and the degradation of insulin-like growth factor 2.
Specifications
| Synonyms | CI-MPR; M6PR; IGF-II receptor; CD222; MPRI; IGF-IIR Uniprot No. P11717 |
| Source | Recombinant Human IGF2R Protein is expressed from Expi293 with His tag and Avi tag at the C-terminal. It contains Glu47-Met1508. |
| Molecular Weight | The protein has a predicted MW of 164.90 kDa. Due to glycosylation, the protein migrates to 165-200 kDa based on Tris-Bis PAGE result. |
| Purity | > 95% as determined by SDS-PAGE and HPLC |
| Formulation | Lyophilized from 0.22 μm filtered solution in PBS (pH 7.4). Normally 8% trehalose is added as protectant before lyophilization. |
| Endotoxin | < 1.0 EU per 1μg of the protein by the LAL method. |
| Reconstitution | Centrifuge tubes before opening. Reconstituting to a concentration more than 100 μg/mL` is recommended (usually we use 1 mg/mL solution for lyophilization). Dissolve the lyophilized protein in distilled water. |
Storage
The products are shipped with ice pack and can be stored at -20℃ for 1 year. 2-7 days, 2 to 8 °C under sterile conditions after reconstitution. 3 months, -20 °C under sterile conditions after reconstitution. Recommend to aliquot the protein into smaller quantities for optimal storage. Please avoid freeze-thaw cycles.
Notes
1.For your safety and health, please wear lab coats and disposable gloves for operation. 2.For research use only!
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