Human LMP2 (HLA-A*02:01) Protein, His-Avi Tag yeasen

$319.00
In stock
SKU
93023ES25
Catalog No.SizePrice (USD)
93023ES2525 μg$319.00
93023ES60100 μg$957.00
93023ES76500 μg$3,349.00

Product Description

The development of molecular probes that selectively inhibit the major catalytic subunit, LMP2, of the immunoproteasome,LMP2-rich cancer cells compared to LMP2-deficient cancer cells are more sensitive to growth inhibition by the LMP2-specific inhibitor, implicating an important role of LMP2 in regulating cell growth of malignant tumors that highly express LMP2.

Specifications

SynonymsMHC; RMF; LMP2; LMP-2; Macropain chain 7; Proteasome chain 7; PSMB9 Uniprot No. A0A140T913(HLA-A*02:01)&P61769(B2M)&CLGGLLTMV]
SourceRecombinant Human LMP2 (HLA-A*02:01) Protein is expressed from Expi293 with His tag and Avi tag at the C-terminal. It contains Gly25-Thr305(HLA-A*02:01),Ile21-Met119(B2M) and CLGGLLTMV peptide
SourceThe protein has a predicted MW of 50.3 kDa. Due to glycosylation, the protein migrates to 52-56 kDa based on Tris-Bis PAGE result.
Purity> 95% as determined by SDS-PAGE and HPLC.
FormulationLyophilized from 0.22 μm filtered solution in PBS (pH 7.4). Normally 8% trehalose is added as protectant before lyophilization.
Endotoxin<1 EU per 1μg of the protein by the LAL method.
ReconstitutionCentrifuge tubes before opening. Reconstituting to a concentration more than 100 μg/mL is recommended (usually we use 1 mg/mL solution for lyophilization). Dissolve the lyophilized protein in distilled water.

Storage

The product should be stored at -25~-15℃ for 1 year from date of receipt. 2-7 days, 2 ~8 °C under sterile conditions after reconstitution. 3 months, -25~-15℃ under sterile conditions after reconstitution. Recommend to aliquot the protein into smaller quantities when first used and avoid repeated freeze-thaw cycles.

Notes

1. Please operate with lab coats and disposable gloves for your safety. 2.This product is for research use only.

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