Product Description
CD30 is a cell membrane protein of the tumor necrosis factor receptor family that regulates proliferation/apoptosis and antibody responses, and is expressed by activated T cells and B cells. CD30 is considered to be a specific diagnostic biomarker for anaplastic large cell lymphoma (ALCL) and classical Hodgkin lymphoma (cHL), and also a biomarker for antibody-drug conjugate targeted therapy.
Specifications
| Synonyms | TNFRSF8,CD30,D1S166E,Ki-1 Uniprot No. P28908 |
| Source | Human CD30 Protein is expressed from HEK293 Cells with His tag at the C-terminal. It contains Phe 19 - Lys 379 |
| Source | The protein has a predicted MW of 39 kDa. And it migrates as 40-50 kDa under reducing (R) condition (SDS-PAGE) due to glycosylation. |
| Purity | > 95% as determined by SDS-PAGE. |
| Formulation | Lyophilized from 0.22 μm filtered solution in PBS (pH 7.4). |
| Endotoxin | <1 EU per 1μg of the protein by the LAL method. |
| Reconstitution | Centrifuge tubes before opening. The concentration of protein solution used for lyophilization is generally 1mg/mL. Dissolve lyophilized protein with sterile water to ensure the concentration is greater than 100 μg/mL. |
Storage
The product should be stored at -25~-15℃ for 1 year. 2-7 days, 2 ~8 °C under sterile conditions after reconstitution. 3 months, -25~-15℃ under sterile conditions after reconstitution. Recommend to aliquot the protein into smaller quantities when first used and avoid repeated freeze-thaw cycles.
Notes
1.Please operate with lab coats and disposable gloves,for your safety. 2.This product is for research use only.