Recombinant ADAR1 Antibody - Primary antibody, specific to ADAR, Rabbit IgG Ab087460-10μl Aladdin
$99.00
In stock
SKU
Ab087460-10μl
Product Information
| Product Name | Recombinant ADAR1 Antibody - Primary antibody, specific to ADAR, Rabbit IgG |
| Short Description | Recombinant; Rabbit anti Human ADAR1 Antibody; WB; Unconjugated |
| Accession | P55265 |
| Gene Symbol | ADAR |
| Gene ID | 103 |
| Form | Liquid |
| Specifications & Purity | ExactAb™, Validated, Recombinant, 0.18 mg/mL |
| SDS Page | 150 kDa |
| Synonyms | 136 kDa double-stranded RNA-binding protein | 136kDa double stranded RNA binding protein | Adar 1 | ADAR | Adar1 | Adenosine deaminase acting on RNA 1 A | Adenosine deaminase RNA specific 1 | Adenosine deaminase RNA specific | Adenosine deaminase that act |
Product Description
Rabbit anti Human ADAR1 Antibody, Recombinant, could be used for WB and so on.
Application:
WB: 1/500-1/1000
Protein Function
Converts multiple adenosines to inosines and creates I/U mismatched base pairs in double-helical RNA substrates without apparent sequence specificity. Has been found to modify more frequently adenosines in AU-rich regions, probably due to the relative ease of melting A/U base pairs as compared to G/C pairs. Functions to modify viral RNA genomes and may be responsible for hypermutation of certain negative-stranded viruses. Edits the messenger RNAs for glutamate receptor (GLUR) subunits by site-selective adenosine deamination. Produces low-level editing at the GLUR-B Q/R site, but edits efficiently at the R/G site and HOTSPOT1. Binds to short interfering RNAs (siRNA) without editing them and suppresses siRNA-mediated RNA interference. Binds to ILF3/NF90 and up-regulates ILF3-mediated gene expression.
Storage and Shipping
| Shipped In | Ice chest + Ice pads |
| Stability and Storage | Store at 4°C short term (1-2 weeks). Store at -20°C long term (24 months). Upon receipt, it is recommended to aliquot. Avoid freeze/thaw cycle. |
| Storage Temp | Store at -20°C,Avoid repeated freezing and thawing |
Additional Information
| Immunogen | A synthetic peptide derived from human ADAR1 (AA 200-250) |
| Isotype | Rabbit IgG |
| Light Chain Type | kappa |
| Positive Control | WB: HeLa, Hep G2 and SK-N-SH cell lysates. |
| Purification Method | Protein A purified |
| Specificity | ADAR |
| X Filter Target ID | ADAR |
| Concentration | 0.18 mg/mL |
Reviews
Write Your Own Review
Related Products
Check items to add to the cart or
