Frozen in 50 mM Na Acetate, pH 5.0, with 1 mM EDTA
Specifications & Purity
Bioactive,ActiBioPure™,Native,High Performance,EnzymoPure™,≥95%(SDS-PAGE),≥200 U/mg protein;Protein concentration: See COA
Biological Activity
≥200 U/mg protein
Synonyms
cathepsin B1 | CTSB | KWE | APPS | CPSB | RECEUP
Product Description
Cathepsin B, a cysteine proteinase, is located in lysosomes and is involved in tissue degradation and restructuring. Specifically, cathepsin B is believed to be involved in the intracellular digestion of extracellular proteins taken up by endocytosis.
Prepared from tissue shown to be non reactive for HBsAg, anti-HCV, anti-HBc, and negative for anti-HIV 1 & 2 by FDA-required tests.
Storage and Shipping
Shipped In
Dry ice packs + Cold packs
Stability and Storage
Store at -80℃ long term (>1 year).Upon receipt, it is recommended to aliquot. Avoid freeze/thaw cycle.
Storage Temp
Store at -80°C,Avoid repeated freezing and thawing
Additional Information
Unit Definition
One unit is defined as the amount of enzyme that hydrolyzes 1 μmol of Z-Arg-Arg-beta-naphthylamide per minute at 40 °C, using 100 mM Na/K phosphate, pH 6.0, with 1.33 mM EDTA and 2 mM DTT as the activation buffer.
Concentration
≥200 U/mg protein;Protein concentration: See COA
1. Yonghui Liu, Zongqian Ren, Yu Zhao, Dong Wan, Jie Pan. (2025) Codelivery of Cell Apoptosis AVPIAQ Peptide and Doxorubicin for Synergistic Cancer Therapy. ACS Applied Bio Materials, [PMID:40442049] [10.1021/acsabm.5c00607]