Recombinant Human C-X-C motif chemokine 11 protein (CXCL11) CSB-AP000731HU CUSABIO
$142.00
In stock
SKU
CSB-AP000731HU
Product Details
| Uniprot No. | O14625 |
| Alternative Names | b R1; b-R1; Beta-R1; betaR1; C-X-C motif chemokine 11; Chemokine (C-X-C motif) ligand 11; Chemokine C-X-C motif ligand 11; CXC11; CXCL11; CXL11_HUMAN; H174; I TAC; I-TAC; Interferon gamma inducible protein 9; Interferon gamma-inducible protein 9; Interferon inducible T cell alpha chemoattractant; Interferon-inducible T-cell a chemoattractant I-TAC; Interferon-inducible T-cell alpha chemoattractant; IP 9; IP-9; IP9; ITAC; MGC102770; SCYB11; SCYB9B; Small inducible cytokine B11; Small inducible cytokine subfamily B (Cys-X-Cys) member 11; Small inducible cytokine subfamily B (Cys-X-Cys) member 9B; Small inducible cytokine subfamily B; member 11; Small inducible cytokine subfamily B; member 9B; Small-inducible cytokine B11 |
| Species | Homo sapiens (Human) |
| Source | E.Coli |
| Expression Region | 22-94aa |
| Purity | >97% as determined by SDS-PAGE. |
| Endotoxin | Less than 1.0 EU/μg as determined by LAL method. |
| Activity | Fully biologically active when compared to standard. The biological activity determined by a chemotaxis bioassay using human IL-2 activated human T-lymphocytes is in a concentration range of 0.1-10 ng/ml. |
| Tag Info | Tag-Free |
| Form | Liquid or Lyophilized powder |
| Buffer | Lyophilized from a 0.2 µm filtered concentrated solution in 20 mM PB, pH 7.4, 100 mM NaCl. |
| Troubleshooting and FAQs | Protein FAQs |
| Lead Time | 5-10 business days |
| Target Names | CXCL11 |
| Research Area | Immunology |
| Complete Sequence | FPMFKRGRCL CIGPGVKAVK VADIEKASIM YPSNNCDKIE VIITLKENKG QRCLNPKSKQ ARLIIKKVER KNF |
| Mol. Weight | 8.3 kDa |
| Protein Length | Full Length of Mature Protein |
| Storage Condition | Store at -20°C/-80°C upon receipt, aliquoting is necessary for mutiple use. Avoid repeated freeze-thaw cycles. |
| Shelf Life | The shelf life is related to many factors, storage state, buffer ingredients, storage temperature and the stability of the protein itself. Generally, the shelf life of liquid form is 6 months at -20°C/-80°C. The shelf life of lyophilized form is 12 months at -20°C/-80°C. |
| Datasheet & COA | Please contact us to get it. |
| Description | CXCL11 (I-TAC) is a potent CXCR3 ligand that drives directional migration of activated T cells, making it central to interferon-γ-mediated inflammatory responses and tumor immune surveillance. This tag-free recombinant human CXCL11, spanning the full mature sequence (22–94 aa), induces chemotaxis of IL-2-activated human T-lymphocytes at 0.1–10 ng/ml, confirming signaling potency suitable for Transwell migration assays, CXCR3 receptor internalization studies, and downstream MAPK or JAK/STAT pathway analyses. Endotoxin levels below 1.0 EU/μg minimize LPS-driven artifacts in sensitive immune cell assays, supporting use in primary T-cell functional experiments, in vivo inflammation or tumor models, and as a reference standard for CXCL11 detection ELISAs. Expressed in *E. coli* and purified to greater than 97% by SDS-PAGE, this protein provides a suitable basis for antibody validation workflows including immunogen use, coating antigen preparation, and Western blot positive controls. |
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