Elab Fluor ® 647 Anti-Mouse TNFα Antibody[XT3.11] (AN00567M) elabscience
$92.00
In stock
SKU
AN00567M
100Tests $ 92.00
Product Details
| Abbre | TNF-α |
| Synonyms | Tumor necrosis factor-α, Cachectin, Necrosin, Macrophage cytotoxic factor, Differentiation inducing factor, TNFSF-2, TNF-a, TNF-alpha |
| Swissprot | P06804 |
| Reactivity | Mouse |
| Host | Rat |
| Clonality | Monoclonal |
| Clone | XT3.11 |
| Isotype | Rat IgG1, κ |
| Isotype Control | Elab Fluor ® 647 Rat IgG1, κ Isotype Control[HRPN] |
| Applications | ICFCM |
| Conjugation | Elab Fluor ® 647 |
| Concentration | 5 μL/Test |
| Buffer | Phosphate buffered solution, pH 7.2, containing 0.09% stabilizer. |
| Cellular Localization | Secreted |
Product Description
Conjugation Information: Elab Fluor ® 647 is designed to be excited by the Red laser (627-640 nm) and detected using an optical filter centered near 670 nm (e.g., a 660/20 nm bandpass filter).
Background: TNF-α is secreted by macrophages, monocytes, neutrophils, T-cells, and NK-cells. Many transformed cell lines also secrete TNF-α. Monomeric mouse TNF-α is a 156 amino acid protein (N-glycosylated) with a reported molecular weight of 17.5 kD. TNF-α forms multimeric complexes; stable trimers are most common in solution. A 26 kD membrane form of TNF-α has also been described. TNF-α binding to surface receptors elicits a wide array of biologic activities including: cytolysis and cytostasis of many tumor cell lines in vitro, hemorrhagic necrosis of tumors in vivo, increased fibroblast proliferation, and enhanced chemotaxis and phagocytosis in neutrophils.
Storage and Shipping
| Storage | This product can be stored at 2-8°C for 24 months. Please protected from prolonged exposure to light and do not freeze. |
| Shipping | Ice bag |
Reviews
Write Your Own Review
Related Products
Check items to add to the cart or
![Biotin Anti-Mouse CD86 Antibody[GL-1] (E-AB-F0994B) elabscience](https://www.biogege.com/media/catalog/product/cache/af3f9de669682211425a7c3e7baf6e62/0/q/E-AB-F0994B_1_8f183fb5a6.jpg)
![Purified Anti-Rat CD44H Antibody[OX-49] (E-AB-F1225A) elabscience](https://www.biogege.com/media/catalog/product/cache/af3f9de669682211425a7c3e7baf6e62/0/q/E-AB-F1225A_1_967c951031.jpg)
