FITC Anti-Human CD8 Antibody[UCHT-4] (AN00427C) elabscience
$50.00
In stock
SKU
AN00427C
100Tests $ 50.00
Product Details
| Abbre | CD8 |
| Synonyms | T8, Leu2 |
| Swissprot | P01732 |
| Reactivity | Human |
| Host | Mouse |
| Clonality | Monoclonal |
| Clone | UCHT-4 |
| Isotype | Mouse IgG1, κ |
| Isotype Control | FITC Mouse IgG1, κ Isotype Control[MOPC-21] |
| Applications | FCM |
| Conjugation | FITC |
| Concentration | 5 μL/Test |
| Buffer | Phosphate buffered solution, pH 7.2, containing 0.09% stabilizer. |
| Cellular Localization | Membrane |
Product Description
Conjugation Information: FITC is designed to be excited by the Blue laser (488 nm) and detected using an optical filter centered near 530 nm (e.g., a 525/40 nm bandpass filter).
Background: CD8a is a 32-34 kD type I glycoprotein. It forms a homodimer (CD8a/a) or heterodimer (CD8a/b) with CD8b. CD8, also known as T8 and Leu2, is a member of the immunoglobulin superfamily found on the majority of thymocytes, a subset of peripheral blood T cells, and NK cells (which express almost exclusively CD8a homodimers). CD8 acts as a co-receptor with MHC class I-restricted T cell receptors in antigen recognition and T cell activation and has been shown to play a role in thymic differentiation. Two domains in CD8a are important for function: the extracellular IgSF domain binds the α3 domain of MHC class I and the cytoplasmic CXCP motif binds the tyrosine kinase p56 Lck
Storage and Shipping
| Storage | This product can be stored at 2-8°C for 24 months. Please protected from prolonged exposure to light and do not freeze. |
| Shipping | Ice bag |
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