CD85 antigen-like family member E, ILT-6, Immunoglobulin-like transcript 6, LILRA3, LIR-4 and Monocyte inhibitory receptor HM43/HM31, Leukocyte immunoglobulin-like receptor 4, Leukocyte immunoglobulin-like receptor subfamily A member 3
Accession
AAH28208.1
Species
Human
Modification
Biotinylated
Form
Lyophilized powder
Formulation
Lyophilized from a 0.2 μm filtered solution of PBS, pH 7.4. Normally 5% - 8% trehalose, mannitol and 0.01% Tween 80 are added as protectants before lyophilization. Please refer to the specific buffer information in the printed manual.
Purity
> 95 % as determined by reducing SDS-PAGE.
Expression Host
HEK293 Cells
Sequence
Gly24-Glu439
Tag
C-His-Avi
Calculated Molecular Weight
47.9 kDa
Observed Molecular Weight
70-90 kDa
Endotoxin
< 1.0 EU per μg of the protein as determined by the LAL method.
Bio-activity
Not validated for activity
Product Description
Background: Leukocyte immunoglobulin-like receptor subfamily A member 3 is also known as CD85 antigen-like family member E, Immunoglobulin-like transcript 6, ILT-6, Leukocyte immunoglobulin-like receptor 4, LIR-4 and Monocyte inhibitory receptor HM43/HM31. In humans, it is encoded by the LILRA3 gene. It acts as soluble receptor for class I MHC antigens. Binds both classical and non-classical HLA class I molecules but with reduced affinities compared to LILRB1 or LILRB2.It is detected in B-cells, natural killer (NK) cells, peripheral blood monocytes and lung.
Storage and Shipping
Storage
Generally, lyophilized proteins are stable for up to 12 months when stored at -20 to -80℃. Reconstituted protein solution can be stored at 4-8℃ for 2-7 days. Aliquots of reconstituted samples are stable at < -20℃ for 3 months.
Shipping
This product is provided as lyophilized powder which is shipped with ice packs.
Reconstitution
Please refer to the printed manual for detailed information.