Purified Anti-Human CD35 Antibody[E11] (E-AB-F1062A) elabscience
$154.00
In stock
SKU
E-AB-F1062A
| Size | Price (USD) |
| 100μg | $154.00 |
| 25μg | $63.00 |
Product Details
| Abbre | CD35 |
| Synonyms | C3BR, C3b/C4b receptor, CD35, CR1, Complement receptor type 1 |
| Swissprot | P17927 |
| Reactivity | Human |
| Host | Mouse |
| Clonality | Monoclonal |
| Clone | E11 |
| Isotype | Mouse IgG1, κ |
| Applications | FCM |
| Conjugation | Unconjugated |
| Concentration | ≥ 1 mg/mL |
| Buffer | Phosphate-buffered solution, pH 7.2, containing 0.05% non-protein stabilizer. Dialyze to completely remove the stabilizer prior to labeling. |
| Purification Method | >98%, Protein A/G purified |
| Immunogen | Recombinant Human CD35 protein |
| Research Areas | Cell Biology, Complement, Immunology, Neuroinflammation, Neuroscience |
| Cellular Localization | Cell membrane |
Product Description
Background: CD35, also known as complement receptor 1 (CR1), is a 220-300 kDa N-glycosylated member of the RCA (regulators of complement activation) family of proteins. CD35 binds and internalizes particles and immune complexes that are opsonized with MBL or complement components C3b, C3i, C4b, or C1q. CD35 additionally protects the cell from complement-mediated lysis by serving as a cofactor for Factor I and inhibiting the C3 and C5 convertases. The extracellular domain (ECD) of human CD35 contains 30 tandem SCR/SUSHI repeats.
Storage and Shipping
| Storage | Store at 4°C valid for 12 months or -20°C valid for long term storage, avoid freeze / thaw cycles. |
| Shipping | Ice bag |
Additional Information
| Verified Samples | Verified Samples in FCM: Human peripheral blood granulocytes cell |
| Dilution | FCM 2 μg/mL(0.5×10^6 -1×10^6 cells) |
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