Recombinant Human FAM3C (C-6His)(Cat. No.:C343) novoprotein
$105.00
In stock
SKU
C343
10μg: $105
50μg: $315
500μg: $1540
1mg: $2200
Description
Recombinant Human Protein FAM3C is produced by our Mammalian expression system and the target gene encoding Gln25-Asp227 is expressed with a 6His tag at the C-terminus.
Product Details
| Item | Details |
| Known As | Protein FAM3C; Interleukin-Like EMT Inducer; FAM3C; ILEI |
| Mol Mass | 23.2 KDa |
| APMol Mass | 20-25 KDa, reducing conditions |
| Formulation Description | Lyophilized from a 0.2 μm filtered solution of 20 mM Citrate, 8% Trehaolse, 5% Mannitol, 0.05% Tween 80, pH4.5. |
| Endotoxin | < 1 EU/µg as determined by LAL test. |
| Reconstitution | Always centrifuge tubes before opening.Do not mix by vortex or pipetting. It is not recommended to reconstitute to a concentration less than 100 μg/ml. Dissolve the lyophilized protein in distilled water. Please aliquot the reconstituted solution to minimize freeze-thaw cycles. |
| Storage | Lyophilized protein should be stored at ≤ -20℃, stable for one year after receipt. Reconstituted protein solution can be stored at 2-8℃ for 2-7 days. Aliquots of reconstituted samples are stable at ≤ -20℃ for 3 months. |
| Shipping | The product is shipped at ambient temperature. Upon receipt, store it immediately at the temperature listed below. |
Background
FAM3C, also called interleukin-like EMT inducer, usually exist in most secretory epithelia. It belongs to the FAM3 family according to their sequence similarities. The up-regulation and/or mislocalization in breast cancer and liver carcinoma cells of FAM3C is strongly correlated with metastasis formation and survival. FAM3C can be involved in retinal laminar formation and promote epithelial to mesenchymal transition.
title: FAM3C activates HSF1 to suppress hepatic gluconeogenesis and attenuate hyperglycemia of type 1 diabetic mice
authors: Zhenzhen Chen, Junpei Wang, Weili Yang, Ji Chen, Yuhong Meng, Biaoqi Feng, Yujing Chi, Bin Geng, Yong Zhou, Qinghua Cui, Jichun Yang
date: 2017
journal: Oncotarget
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