Recombinant Human PKCE (C-6His)(Cat. No.:C165) novoprotein
$105.00
In stock
SKU
C165
10μg: $105
50μg: $315
500μg: $1540
1mg: $2200
Description
Recombinant Human PKC Epsilon is produced by our E.coli expression system and the target gene encoding Gln580-Pro737 is expressed with a 6His tag at the C-terminus.
Product Details
| Item | Details |
| Known As | Protein Kinase C Epsilon Type; nPKC-Epsilon; PRKCE; PKCE |
| Mol Mass | 19.64 KDa |
| APMol Mass | 24 KDa, reducing conditions |
| Formulation Description | Supplied as a 0.2 μm filtered solution of 20mM Tris-HCl, 150mM NaCl, 5% Trehalose, 1mM DTT, 0.03% Tween 80, pH 8.0. |
| Endotoxin | < 1 EU/µg as determined by LAL test. |
| Storage | Store at ≤-70°C, stable for 6 months after receipt. Store at ≤-70°C, stable for 3 months under sterile conditions after opening. Please minimize freeze-thaw cycles. |
| Shipping | The product is shipped on dry ice/polar packs. Upon receipt, store it immediately at the temperature listed below. |
Background
Protein Kinase C Epsilon type is a member of the serine- and threonine-specific protein kinase family that can be activated by calcium and the second messenger diacylglycerol. Protein Kinase C Epsilon contains these domains: one AGC-kinase C-terminal domain, one C2 domain, one protein kinase domain and two phorbol-ester/DAG-type zinc fingers. Protein Kinase C Epsilon phosphorylate a variety of protein targets and has been identified to participate in diverse cellular signaling pathways. It has many different cellular functions, such as neuron channel activation, apoptosis, cardioprotection from ischemia, heat shock response, as well as insulin exocytosis. Protein Kinase C Epsilon also serves as the receptor for phorbol esters, a class of tumor promoters.
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