Recombinant Human CEACAM8 (C-6His)(Cat. No.:C583) novoprotein

$105.00
In stock
SKU
C583
10μg: $105 50μg: $315 500μg: $1540 1mg: $2200

Description

Recombinant Human Carcinoembryonic Antigen-Related Cell Adhesion Molecule 8 is produced by our Mammalian expression system and the target gene encoding Gln35-His141 is expressed with a 6His tag at the C-terminus.

Product Details

ItemDetails
Known AsCarcinoembryonic Antigen-Related Cell Adhesion Molecule 8; CD67 Antigen; Carcinoembryonic Antigen CGM6; Non-Specific Cross-Reacting Antigen NCA-95; CD66b; CEACAM8; CGM6
Mol Mass13.03 KDa
APMol Mass17-25 KDa, reducing conditions
Formulation DescriptionLyophilized from a 0.2 μm filtered solution of 20mM PB, 150mM NaCl, pH 7.4.
Endotoxin< 1 EU/µg as determined by LAL test.
ReconstitutionAlways centrifuge tubes before opening.Do not mix by vortex or pipetting.
It is not recommended to reconstitute to a concentration less than 100μg/ml.
Dissolve the lyophilized protein in distilled water.
Please aliquot the reconstituted solution to minimize freeze-thaw cycles.
StorageLyophilized protein should be stored at ≤ -20°C, stable for one year after receipt.
Reconstituted protein solution can be stored at 2-8°C for 2-7 days.
Aliquots of reconstituted samples are stable at ≤ -20°C for 3 months.
ShippingThe product is shipped at ambient temperature.
Upon receipt, store it immediately at the temperature listed below.

Background

Carcinoembryonic Antigen-Related Cell Adhesion Molecule 8 (CEACAM8) is a single chain, GPI-anchored, highly glycosylated protein which belongs to the immunoglobulin superfamily and the carcinoembryonic antigen(CEA) family. CEACAM8 is expressed by neutrophils and eosinophils, and serves as a binding partner for CEACAM-6 and Galectin-3. It contains two Ig-like C2-type (immunoglobulin-like) domains and one Ig-like V-type (immunoglobulin-like) domain. Mature human CEACAM8 is a 287 amino acid GPI-linked glycoprotein. CEACAM family members are a set of widely expressed proteins involved in several biological functions, including cell adhesion, migration, signal transduction, and the regulation of gene expression. Abnormal overexpression and downregulation of some CEACAMs have been described in tumor cells.

title: The analytical performance and clinical application of magnetic microparticle chemiluminescent immunoassay for the determination of serum CEACAM1
authors: Boke Zhang, Haixia Huang, Qingyong Ding, Chengtao Ding, Qingbao Wang, Jun Zhu, Changcheng Yang
date: 2025/11/13
journal: JOURNAL OF PHARMACEUTICAL AND BIOMEDICAL ANALYSIS

MDSD

Datasheet

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