Anti-Human IL-6 Antibody (SIL_bio, Research Grade)(Cat. No.:NC326) novoprotein
$50.00
In stock
SKU
NC326
50μg: Inquiry
1mg: Inquiry
Description
Human IL-6 Antibody (Siltuximab, Research Grade) is a human monoclonal antibody human IgG1 and is produced by our Mammalian expression system.
Product Details
| Item | Details |
| Isotype | Human IgG1 |
| Mol Mass | 49.3&23.1 KDa |
| Formulation Description | Supplied as a 0.2 μm filtered solution of 20 mM Histidine, 8% Sucrose, 0.06% Tween80, pH5.0. |
| Endotoxin | < 1 EU/µg as determined by LAL test. |
| Shipping | The product is shipped on dry ice/polar packs. Upon receipt, store it immediately at the temperature listed below. |
| Storage | Store at ≤ -20℃, stable for 12 months after receipt. Please minimize freeze-thaw cycles. |
Background
Cytokines of the IL6/GCSF/MGF family are glycoproteins of about 170 to 180 amino acid residues that contain four conserved cysteine residues involved in two disulfide bonds. They have a compact, globular fold (similar to other interleukins), stabilized by the 2 disulfide bonds. One half of the structure is dominated by a 4 alpha-helix bundle with a left-handed twist; the helices are anti-parallel, with 2 overhand connections, which fall into a 2-stranded anti-parallel beta-sheet. The fourth alpha helix is important to the biological activity of the molecule. Interleukin-6 (IL-6) is an important proinflammatory and immunoregulatory cytokine expressed by various cells. Interleukin-6 has been shown to inhibit the growth of early stage and to promote the proliferation of advanced stage melanoma cells in vitro.
MDSD
Reviews
Write Your Own Review
Related Products
Check items to add to the cart or
