C8G Recombinant monoclonal antibody 85652-1-RR proteintech
$149.00
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85652-1-RR
| Catalog Number | 85652-1-RR |
| Synonyms | C8C |
| Host | Rabbit |
| Reactivity | human |
| Form | Liquid |
| Formulation | PBS, Azide, Glycerol |
| Applications | WB, ELISA |
| Host / Isotype | Rabbit / IgG |
| Tested Applications — Positive WB detected in | human milk, human plasma, human placenta |
| Recommended Dilutions — Western Blot (WB) | WB : 1:500-1:2000 |
| Positive WB detected in | human milk, human plasma, human placenta |
| Western Blot (WB) | WB : 1:500-1:2000 |
| Tested Reactivity | human |
| Class | Recombinant |
| Type | Antibody |
| Immunogen | CatNo: Ag18261 Product name: Recombinant human C8G protein Source: e coli. -derived, PET28a Tag: 6*His Domain: 1-202 aa of BC113626 Sequence: MLPPGTATLLTLLLAAGSLGQKPQRPRRPASPISTIQPKANFDAQQFAGTWLLVAVGSACRFLQEQGHRAEATTLHVAPQGTAMAVSTFRKLDGICWQVRQLYGDTGVLGRFLLQARGARGAVNVVVAETDYQSFAVLYLERAGQLSVKLYARSLPVSDSVLSGFEQRVQEAHLTEDQIFYFPKYGFCEAADQFHVLDEVRR Predict reactive species |
| Full Name | complement component 8, gamma polypeptide |
| Calculated Molecular Weight | 202 aa, 22 kDa |
| Observed Molecular Weight | 18-22 kDa |
| GenBank Accession Number | BC113626 |
| Gene Symbol | C8G |
| Gene ID (NCBI) | 733 |
| RRID | AB_3744269 |
| Conjugate | Unconjugated |
| Purification Method | Protein A purification |
| UNIPROT ID | P07360 |
| Storage Buffer | PBS with 0.02% sodium azide and 50% glycerol, pH 7.3. |
| Storage Conditions | Store at -20°C. Stable for one year after shipment. Aliquoting is unnecessary for -20 o C storage. 20ul sizes contain 0.1% BSA. |
| WB protocol for C8G antibody 85652-1-RR | Download protocol |
| Citations | - |
| Dilutions | WB : 1:500-1:2000 |
| Isotype | IgG |
| Clonality | Recombinant |
| Clone Number | 242479G11 |
| Conjugation | Unconjugated |
The gamma chain of complement component 8 (C8G) is one of three different subunits (alpha, beta, and gamma) of the eighth complement component (C8), which is a component of the MAC (membrane attack complex) (PMID:33382892). Although the roles of C8A and C8B are directly associated with MAC formation, C8G is not essential in the assembly and activity of the MAC (PMID:11960635). Moreover, C8G was shown to inhibit neuroinflammation by interfering with the sphingosine-1-phosphate (S1P)-S1PR2 interaction (PMID:34149451). Protocols Product Specific Protocols WB protocol for C8G antibody 85652-1-RR Download protocol Standard Protocols Click here to view our Standard Protocols
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