CCT2 Monoclonal antibody, PBS Only 68214-1-PBS proteintech
$699.00
In stock
SKU
68214-1-PBS
| Catalog Number | 68214-1-PBS |
| Synonyms | 99D8.1, CCT beta, CCTB, CCT-beta, Chaperonin containing T-complex polypeptide 1 subunit 2 |
| Host | Mouse |
| Reactivity | human, mouse, rat, pig, rabbit |
| Form | Liquid |
| Formulation | PBS Only |
| Applications | WB, IF/ICC, ELISA |
| Host / Isotype | Mouse / IgG1 |
| Tested Reactivity | human, mouse, rat, pig, rabbit |
| Class | Monoclonal |
| Type | Antibody |
| Immunogen | CatNo: Ag19264 Product name: Recombinant human CCT2 protein Source: e coli. -derived, PET28a Tag: 6*His Domain: 186-535 aa of BC113516 Sequence: AVLRLKGSGNLEAIHIIKKLGGSLADSYLDEGFLLDKKIGVNQPKRIENAKILIANTGMDTDKIKIFGSRVRVDSTAKVAEIEHAEKEKMKEKVERILKHGINCFINRQLIYNYPEQLFGAAGVMAIEHADFAGVERLALVTGGEIASTFDHPELVKLGSCKLIEEVMIGEDKLIHFSGVALGEACTIVLRGATQQILDEAERSLHDALCVLAQTVKDSRTVYGGGCSEMLMAHAVTQLANRTPGKEAVAMESYAKALRMLPTIIADNAGYDSADLVAQLRAAHSEGNTTAGLDMREGTIGDMAILGITESFQVKRQVLLSAAEAAEVILRVDNIIKAAPRKRVPDHHPC Predict reactive species |
| Full Name | chaperonin containing TCP1, subunit 2 (beta) |
| Calculated Molecular Weight | 535 aa, 57 kDa |
| Observed Molecular Weight | 50-58 kDa |
| GenBank Accession Number | BC113516 |
| Gene Symbol | CCT2 |
| Gene ID (NCBI) | 10576 |
| RRID | AB_2935302 |
| Conjugate | Unconjugated |
| Purification Method | Protein G purification |
| UNIPROT ID | P78371 |
| Storage Buffer | PBS only, pH 7.3. |
| Storage Conditions | Store at -80°C. |
| Citations | - |
| Isotype | IgG1 |
| Clonality | Monoclonal |
| Clone Number | 2H6C7 |
| Conjugation | Unconjugated |
CCT2 is a gene encoding a molecular chaperone that is a member of the chaperonin containing TCP1 complex (CCT), also known as the TCP1 ring complex (TRiC). The switch of CCT2ʹs role from a chaperonin to a specific aggrephagy receptor is achieved by CCT2 monomer formation. CCT2 functions independently of ubiquitin and the TRiC complex to facilitate the autophagic clearance of solid protein aggregates. CCT2 has 2 isoforms with the molecular mass of 53 and 57 kDa. (PMID: 35699934)
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