CoraLite® Plus 405 Anti-Human CD25/IL-2RA (BC96) CL405-65096 proteintech

$159.00
In stock
SKU
CL405-65096
Catalog No.SizePrice (USD)
CL405-65096-100TESTS100tests$159.00
Catalog NumberCL405-65096
SynonymsCD25, BC96, IL 2 RA, IL 2 receptor subunit alpha, IL 2R subunit alpha
HostMouse
ReactivityHuman,Cynomolgus monkey
Reactivityhuman, cynomolgus monkey
FormLiquid
FormulationPBS, Azide, BSA
ApplicationsFC
Host / IsotypeMouse / IgG1, kappa
Tested Applications — Positive FC detected inPHA treated human PBMCs
Positive FC detected inPHA treated human PBMCs
Flow Cytometry (FC)FC : 5 ul per 10^6 cells in 100 μl suspension
Tested ReactivityHuman,Cynomolgus monkey
ClassMonoclonal
TypeAntibody
ImmunogenN/A Predict reactive species
Full Nameinterleukin 2 receptor, alpha
Calculated Molecular Weight272 aa, 31 kDa
GenBank Accession NumberBC156627
Gene SymbolIL2RA
Gene ID (NCBI)3559
RRIDAB_3672384
ConjugateCoraLite® Plus 405 Fluorescent Dye
Excitation/Emission Maxima Wavelengths399 nm / 422 nm
Excitation LaserViolet Laser (405 nm)
Purification MethodAffinity purification
UNIPROT IDP01589
Storage BufferPBS with 0.09% sodium azide and 0.5% BSA, pH 7.3.
Storage ConditionsStore at 2-8°C. Avoid exposure to light. Stable for one year after shipment.
FC protocol for CL Plus 405 CD25/IL-2RA antibody CL405-65096Download protocol
Citations-
IsotypeIgG1, kappa
ClonalityMonoclonal
Clone NumberBC96
ConjugationCoraLite® Plus 405

Proliferation of T lymphocytes is triggered by the interaction of IL-2 with its specific receptor following T lymphocyte activation. The receptor for IL-2 has three forms, generated by different combinations of three different proteins, the alpha chain (IL-2R alpha), the beta chain (IL-2R beta), and the gamma chain (IL-2R gamma) (PMID: 8476561). IL-2R alpha (also known as CD25) is a type I transmembrane protein present on activated T cells, activated B cells, some thymocytes, myeloid precursors, and oligodendrocytes. CD25 is also found on natural CD4+Foxp3+ Treg cells and a subset of human CD4+ memory T cells (PMID: 22585674). Protocols Product Specific Protocols FC protocol for CL Plus 405 CD25/IL-2RA antibody CL405-65096 Download protocol Standard Protocols Click here to view our Standard Protocols

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