CLEC14A Polyclonal antibody 23964-1-AP proteintech
$149.00
In stock
SKU
23964-1-AP
| Catalog Number | 23964-1-AP |
| Synonyms | UNQ236/PRO269, EGFR-5, C-type lectin domain family 14 member A, CEG1, C14orf27 |
| Host | Rabbit |
| Reactivity | human, mouse, rat |
| Form | Liquid |
| Formulation | PBS, Azide, Glycerol |
| Applications | WB, IHC, ELISA |
| Applications | WB, ELISA |
| Host / Isotype | Rabbit / IgG |
| Tested Applications — Positive WB detected in | mouse brain tissue, mouse skeletal muscle tissue, human heart tissue, rat brain tissue |
| Recommended Dilutions — Western Blot (WB) | WB : 1:1000-1:4000 |
| Positive WB detected in | mouse brain tissue, mouse skeletal muscle tissue, human heart tissue, rat brain tissue |
| Western Blot (WB) | WB : 1:1000-1:4000 |
| Tested Reactivity | human, mouse, rat |
| Cited Reactivity | human, mouse |
| Class | Polyclonal |
| Type | Antibody |
| Immunogen | CatNo: Ag21081 Product name: Recombinant human CLEC14A protein Source: e coli. -derived, PET30a Tag: 6*His Domain: 1-349 aa of BC031567 Sequence: MRPAFALCLLWQALWPGPGGGEHPTADRAGCSASGACYSLHHATMKRQAAEEACILRGGALSTVRAGAELRAVLALLRAGPGPGGGSKDLLFWVALERRRSHCTLENEPLRGFSWLSSDPGGLESDTLQWVEEPQRSCTARRCAVLQATGGVEPAGWKEMRCHLRANGYLCKYQFEVLCPAPRPGAASNLSYRAPFQLHSAALDFSPPGTEVSALCRGQLPISVTCIADEIGARWDKLSGDVLCPCPGRYLRAGKCAELPNCLDDLGGFACECATGFELGKDGRSCVTSGEGQPTLGGTGVPTRRPPATATSPVPQRTWPIRVDEKLGETPLVPEQDNSVTSIPEIPRW Predict reactive species |
| Full Name | C-type lectin domain family 14, member A |
| Calculated Molecular Weight | 490 aa, 52 kDa |
| Observed Molecular Weight | 52 kDa, 100 kDa |
| GenBank Accession Number | BC031567 |
| Gene Symbol | CLEC14A |
| Gene ID (NCBI) | 161198 |
| RRID | AB_2879377 |
| Conjugate | Unconjugated |
| Purification Method | Antigen Affinity purified |
| UNIPROT ID | Q86T13 |
| Storage Buffer | PBS with 0.02% sodium azide and 50% glycerol, pH 7.3. |
| Storage Conditions | Store at -20°C. Stable for one year after shipment. Aliquoting is unnecessary for -20 o C storage. 20ul sizes contain 0.1% BSA. |
| WB protocol for CLEC14A antibody 23964-1-AP | Download protocol |
| human,mouse | WB,IHC FASEB J CLEC14A protects against podocyte injury in mice with adriamycin nephropathy. Authors - Zeyu Su View Article |
| Citations | 2 |
| Dilutions | WB : 1:1000-1:4000 |
| Isotype | IgG |
| Clonality | Polyclonal |
| Clone Number | - |
| Conjugation | Unconjugated |
CLEC14A is a single-pass type I transmembrane protein whose extracellular domain consists of a C-type lectin-like domain (CTLD), a series of EGF-like domains, and a sushi-like domain (PMID: 23644659). CLEC14A is a member of the C-type lectin domain superfamily that also includes endosialin, thrombomodulin and CD93 (PMID: 16336259). It has been reported that CLEC14A is specifically expressed in endothelial cells and mediates cell to cell adhesion (PMID: 21095181). CLEC14A may be involved in tumor angiogenesis (PMID: 21706054; 23644659). Protocols Product Specific Protocols WB protocol for CLEC14A antibody 23964-1-AP Download protocol Standard Protocols Click here to view our Standard Protocols
Publications
- CLEC14A protects against podocyte injury in mice with adriamycin nephropathy.
Journal: FASEB J | Authors: Zeyu Su | Species: human,mouse | Application: WB,IHC - Alpha-difluoromethylornithine suppresses angiogenesis via the FLI1-CLEC14A-VEGFC pathway in retinal endothelial cells.
Journal: Biochem Biophys Res Commun | Authors: Jia-Qi Pan
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