CYP2E1-Specific Monoclonal antibody, PBS Only 67263-1-PBS proteintech
$699.00
In stock
SKU
67263-1-PBS
| Catalog Number | 67263-1-PBS |
| Synonyms | CYP2E1, 1F12G7, 4-nitrophenol 2-hydroxylase, CPE1, CYP2E |
| Host | Mouse |
| Reactivity | mouse, rat, pig |
| Form | Liquid |
| Formulation | PBS Only |
| Applications | WB, IHC, IF-P, IF-Fro, Indirect ELISA |
| Host / Isotype | Mouse / IgG2b |
| Tested Reactivity | mouse, rat, pig |
| Class | Monoclonal |
| Type | Antibody |
| Immunogen | Peptide Predict reactive species |
| Full Name | cytochrome P450, family 2, subfamily E, polypeptide 1 |
| Calculated Molecular Weight | 57 kDa |
| Observed Molecular Weight | 50-57 kDa |
| GenBank Accession Number | NM_000773 |
| Gene Symbol | CYP2E1 |
| Gene ID (NCBI) | 1571 |
| RRID | AB_2882534 |
| Conjugate | Unconjugated |
| Purification Method | Protein A purification |
| UNIPROT ID | P05181 |
| Storage Buffer | PBS only, pH 7.3. |
| Storage Conditions | Store at -80°C. |
| Citations | - |
| Isotype | IgG2b |
| Clonality | Monoclonal |
| Clone Number | 1F12G7 |
| Conjugation | Unconjugated |
CYP2E1, also named as CYPIIE1, 4-nitrophenol 2-hydroxylase, P450-J and CYP2E, belongs to the cytochrome P450 family. CYP2E1 metabolizes several precarcinogens, drugs, and solvents to reactive metabolites. It inactivates a number of drugs and xenobiotics and also bioactivates many xenobiotic substrates to their hepatotoxic or carcinogenic forms. CYP2E1 catalyze the reaction: 4-nitrophenol + NADPH + O2 = 4-nitrocatechol + NADP+ + H2O. CYP2E1 can be detected as 50-57 kDa(full-length) and ~40 kDa(N-terminal signal peptide cleaved) (PMID: 21130154). The antibody is specific to CYP2E1.
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