FGL2 Monoclonal antibody 67152-1-Ig proteintech
$149.00
In stock
SKU
67152-1-Ig
| Catalog Number | 67152-1-Ig |
| Synonyms | FGL2, FGL-2, fibrinogen like 2, Fibrinogen like protein 2, Fibroleukin, pT49, T49 |
| Host | Mouse |
| Reactivity | Human, mouse and More (1) |
| Reactivity | human, mouse |
| Form | Liquid |
| Formulation | PBS, Azide, Glycerol |
| Applications | WB, IF-P, ELISA |
| Host / Isotype | Mouse / IgG2b |
| Tested Applications — Positive WB detected in | THP-1 cells, Jurkat cells |
| Tested Applications — Positive IF-P detected in | mouse spleen tissue |
| Recommended Dilutions — Western Blot (WB) | WB : 1:2000-1:10000 |
| Recommended Dilutions — Immunofluorescence (IF)-P | IF-P : 1:200-1:800 |
| Positive WB detected in | THP-1 cells, Jurkat cells |
| Positive IF-P detected in | mouse spleen tissue |
| Western Blot (WB) | WB : 1:2000-1:10000 |
| Immunofluorescence (IF)-P | IF-P : 1:200-1:800 |
| Tested Reactivity | Human, mouse |
| Cited Reactivity | human, mouse |
| Class | Monoclonal |
| Type | Antibody |
| Immunogen | CatNo: Ag28619 Product name: Recombinant human FGL2 protein Source: e coli. -derived, PET28a Tag: 6*His Domain: 1-148 aa of BC017813 Sequence: MKLANWYWLSSAVLAAYGFLVVANNETEEIKDERAKDVCPVRLESRGKCEEAGECPYQVSLPPLTIQLPKQFSRIEEVFKEVQNLKEIVNSLKKSCQDCKLQADDNGDPGRNGLLLPSTGAPGEVGDNRVRELESEVNKLSSELKFIF Predict reactive species |
| Full Name | fibrinogen-like 2 |
| Calculated Molecular Weight | 50 kDa |
| Observed Molecular Weight | 70 kDa |
| GenBank Accession Number | BC017813 |
| Gene Symbol | FGL2 |
| Gene ID (NCBI) | 10875 |
| RRID | AB_2882449 |
| Conjugate | Unconjugated |
| Purification Method | Protein A purification |
| UNIPROT ID | Q14314 |
| Storage Buffer | PBS with 0.02% sodium azide and 50% glycerol, pH 7.3. |
| Storage Conditions | Store at -20°C. Stable for one year after shipment. Aliquoting is unnecessary for -20 o C storage. 20ul sizes contain 0.1% BSA. |
| IF protocol for FGL2 antibody 67152-1-Ig | Download protocol |
| WB protocol for FGL2 antibody 67152-1-Ig | Download protocol |
| human | WB J Clin Invest Targeting fibrinogen-like protein 1 enhances immunotherapy in hepatocellular carcinoma Authors - Mingen Lin View Article |
| mouse | WB Cell Rep FBXO38 mediates FGL1 ubiquitination and degradation to enhance cancer immunity and suppress inflammation Authors - Tongguan Tian View Article |
| Citations | 2 |
| Dilutions | WB : 1:2000-1:10000 IF-P : 1:200-1:800 |
| Isotype | IgG2b |
| Clonality | Monoclonal |
| Clone Number | 2C9C5 |
| Conjugation | Unconjugated |
FGL2 (fibrinogen like protein 2) is a 70 kDa glycoprotein that belongs to the fibrinogen-related superfamily of proteins which are involved in coagulation, cell adhesion, and transendothelial migration. FGL2 is an important immune regulator of both innate and adaptive response. It is present on the surface of macrophages and endothelial cells, and can be constitutively secreted by CD4+ CD8+ T cell. FGL2 forms a tetrameric complex which is stabilized by interchain disulfide bonds and it exerts immunosuppressive effects on both T cell proliferation and dendritic cell maturation. The protein may play a role in physiologic functions at mucosal sites. Protocols Product Specific Protocols IF protocol for FGL2 antibody 67152-1-Ig Download protocol WB protocol for FGL2 antibody 67152-1-Ig Download protocol Standard Protocols Click here to view our Standard Protocols
Publications
- Targeting fibrinogen-like protein 1 enhances immunotherapy in hepatocellular carcinoma
Journal: J Clin Invest | Authors: Mingen Lin | Species: human | Application: WB - FBXO38 mediates FGL1 ubiquitination and degradation to enhance cancer immunity and suppress inflammation
Journal: Cell Rep | Authors: Tongguan Tian | Species: mouse | Application: WB
Reviews
Write Your Own Review
Related Products
Check items to add to the cart or
