GADD45A Recombinant monoclonal antibody, PBS Only (Capture) 84376-4-PBS proteintech
$699.00
In stock
SKU
84376-4-PBS
| Catalog Number | 84376-4-PBS |
| Synonyms | 241597H4, DDIT 1, DDIT1, DDIT-1, DNA damage-inducible transcript 1 protein |
| Host | Rabbit |
| Reactivity | human, mouse |
| Form | Liquid |
| Formulation | PBS Only |
| Applications | WB, FC (Intra), Cytometric bead array, Indirect ELISA |
| Host / Isotype | Rabbit / IgG |
| Tested Reactivity | human, mouse |
| Class | Recombinant |
| Type | Antibody |
| Immunogen | CatNo: Ag4687 Product name: Recombinant human GADD45A protein Source: e coli. -derived, PGEX-4T Tag: GST Domain: 5-165 aa of BC011757 Sequence: EFSAGEQKTERMDKVGDALEEVLSKALSQRTITVGVYEAAKLLNVDPDNVVLCLLAADEDDDRDVALQIHFTLIQAFCCENDINILRVSNPGRLAELLLLETDAGPAASEGAEQPPDLHCVLVTNPHSSQWKDPALSQLICFCRESRYMDQWVPVINLPER Predict reactive species |
| Full Name | growth arrest and DNA-damage-inducible, alpha |
| Calculated Molecular Weight | 165 aa, 18 kDa |
| Observed Molecular Weight | 14-18 kDa, 28-36 kDa |
| GenBank Accession Number | BC011757 |
| Gene Symbol | GADD45A |
| Gene ID (NCBI) | 1647 |
| RRID | AB_3671913 |
| Conjugate | Unconjugated |
| Purification Method | Protein A purification |
| UNIPROT ID | P24522 |
| Storage Buffer | PBS only, pH 7.3. |
| Storage Conditions | Store at -80°C. |
| Citations | - |
| Isotype | IgG |
| Clonality | Recombinant |
| Clone Number | 241597H4 |
| Conjugation | Unconjugated |
GADD45A, also named as DDIT1 and GADD45, belongs to the GADD45 family. It binds to proliferating cell nuclear antigen. GADD45A may affect PCNA interaction with some CDK (cell division protein kinase) complexes; stimulates DNA excision repair in vitro and inhibits entry of cells into S phase. GADD45A plays an essential role in active DNA demethylation during terminal osteogenic differentiation of adipose-derived mesenchymal stem cells. GADD45A has Dimer (~28-36 kDa) and Monomer (14-18 kDa) forms (PMID:11498536).