GADD45A Recombinant monoclonal antibody, PBS Only (Capture) 84376-4-PBS proteintech

$699.00
In stock
SKU
84376-4-PBS
Catalog No.SizePrice (USD)
84376-4-PBS-100UG100 μg$699.00
Catalog Number84376-4-PBS
Synonyms241597H4, DDIT 1, DDIT1, DDIT-1, DNA damage-inducible transcript 1 protein
HostRabbit
Reactivityhuman, mouse
FormLiquid
FormulationPBS Only
ApplicationsWB, FC (Intra), Cytometric bead array, Indirect ELISA
Host / IsotypeRabbit / IgG
Tested Reactivityhuman, mouse
ClassRecombinant
TypeAntibody
ImmunogenCatNo: Ag4687 Product name: Recombinant human GADD45A protein Source: e coli. -derived, PGEX-4T Tag: GST Domain: 5-165 aa of BC011757 Sequence: EFSAGEQKTERMDKVGDALEEVLSKALSQRTITVGVYEAAKLLNVDPDNVVLCLLAADEDDDRDVALQIHFTLIQAFCCENDINILRVSNPGRLAELLLLETDAGPAASEGAEQPPDLHCVLVTNPHSSQWKDPALSQLICFCRESRYMDQWVPVINLPER Predict reactive species
Full Namegrowth arrest and DNA-damage-inducible, alpha
Calculated Molecular Weight165 aa, 18 kDa
Observed Molecular Weight14-18 kDa, 28-36 kDa
GenBank Accession NumberBC011757
Gene SymbolGADD45A
Gene ID (NCBI)1647
RRIDAB_3671913
ConjugateUnconjugated
Purification MethodProtein A purification
UNIPROT IDP24522
Storage BufferPBS only, pH 7.3.
Storage ConditionsStore at -80°C.
Citations-
IsotypeIgG
ClonalityRecombinant
Clone Number241597H4
ConjugationUnconjugated

GADD45A, also named as DDIT1 and GADD45, belongs to the GADD45 family. It binds to proliferating cell nuclear antigen. GADD45A may affect PCNA interaction with some CDK (cell division protein kinase) complexes; stimulates DNA excision repair in vitro and inhibits entry of cells into S phase. GADD45A plays an essential role in active DNA demethylation during terminal osteogenic differentiation of adipose-derived mesenchymal stem cells. GADD45A has Dimer (~28-36 kDa) and Monomer (14-18 kDa) forms (PMID:11498536).

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