| Product name | IHCeasy UBE2C Ready-To-Use IHC Kit |
| Synonyms | UbcH10, UB E2C, EC:2.3.2.24, EC:2.3.2.23, E2 ubiquitin-conjugating enzyme C |
| Reactivity | Human, Mouse, Rat |
| Host / Isotype | United States |
| Sample type | FFPE tissue |
| Assay type | Immunohistochemistry |
| Primary antibody type | Rabbit Polyclonal |
| Secondary antibody type | Polymer-HRP-Goat anti-Rabbit |
| Component | Size Concentration |
| Antigen Retrieval Buffer | 100 mL 50× |
| Washing Buffer | 100 mL ×2 20× |
| Blocking Buffer | 5 mL RTU |
| Primary Antibody | 5 mL RTU |
| Secondary Antibody | 5 mL RTU |
| Chromogen Component A | 0.2 mL RTU |
| Chromogen Component B | 4 mL RTU |
| Signal Enhancer | 5 mL RTU |
| Counter Staining Reagent | 5 mL RTU |
| Mounting Media | 5 mL RTU |
| Datasheet | 1 Copy |
| Manual | 1 Copy |
| Storage Instructions | All the reagents are stored at 2-8°C. The kit is stable for 6 months from the date of receipt. |
UBE2C(Ubiquitin-conjugating enzyme E2 C) is also known as UBCH10 and belongs to the ubiquitin-conjugating enzyme family. It is highly expressed in a variety of human primary tumors, and it is able to promote cell proliferation and malignant transformation. UBE2C, along with the E3 ligase of the anaphasepromoting complex (APC), catalyzes the ubiquitination of mitotic cyclins A and B, as well as securin. UBE2C is essential for cell cycle progression, and mutation of its active site cysteine confers a dominant-negative phenotype. Properties Storage Instructions All the reagents are stored at 2-8°C. The kit is stable for 6 months from the date of receipt. Synonyms UbcH10, UB E2C, EC:2.3.2.24, EC:2.3.2.23, E2 ubiquitin-conjugating enzyme C × Select download options English Czech Danish German Spanish Finnish French Hungarian Italian Lithuanian Dutch Norwegian-Bokmol Polish Portuguese Slovak Swedish Download