NEDD9 Recombinant monoclonal antibody, PBS Only (Capture) 83362-2-PBS proteintech
$699.00
In stock
SKU
83362-2-PBS
| Catalog Number | 83362-2-PBS |
| Synonyms | 240310F8, CASL, CAS-L, CRK-associated substrate-related protein, Enhancer of filamentation 1 p55 |
| Host | Rabbit |
| Reactivity | human |
| Form | Liquid |
| Formulation | PBS Only |
| Applications | WB, IF/ICC, Cytometric bead array, Indirect ELISA |
| Host / Isotype | Rabbit / IgG |
| Tested Reactivity | human |
| Class | Recombinant |
| Type | Antibody |
| Immunogen | CatNo: Ag34170 Product name: Recombinant human NEDD9 protein Source: e coli. -derived, PGEX-4T Tag: GST Domain: 227-458 aa of BC040207 Sequence: PSACRDEAGLREKDYDFPPPMRQAGRPDLRPEGVYDIPPTCTKPAGKDLHVKYNCDIPGAAEPVARRHQSLSPNHPPPQLGQSVGSQNDAYDVPRGVQFLEPPAETSEKANPQERDGVYDVPLHNPPDAKGSRDLVDGINRLSFSSTGSTRSNMSTSSTSSKESSLSASPAQDKRLFLDPDTAIERLQRLQQALEMGVSSLMALVTTDWRCYGYMERHINEIRTAVDKVELF Predict reactive species |
| Full Name | neural precursor cell expressed, developmentally down-regulated 9 |
| Calculated Molecular Weight | 834 aa, 93 kDa |
| Observed Molecular Weight | 105 kDa, 115 kDa |
| GenBank Accession Number | BC040207 |
| Gene Symbol | NEDD9 |
| Gene ID (NCBI) | 4739 |
| RRID | AB_3671016 |
| Conjugate | Unconjugated |
| Purification Method | Protein A purification |
| UNIPROT ID | Q14511 |
| Storage Buffer | PBS only, pH 7.3. |
| Storage Conditions | Store at -80°C. |
| Citations | - |
| Isotype | IgG |
| Clonality | Recombinant |
| Clone Number | 240310F8 |
| Conjugation | Unconjugated |
NEDD9, also known as CASL, HEF1, contains an N-terminal Src homology (SH) 3 domain and an adjacent domain composed of multiple SH2-binding motifs(PMID: 8668148). Cell cycle-regulated processing produces four isoforms: p115, p105, p65, and p55. Isoform p115 arises from p105 phosphorylation and appears later in the cell cycle. Isoform p55 arises from p105 as a result of cleavage at a caspase cleavage-related site and it appears specifically at mitosis. p105 and p115 are predominantly cytoplasmic and associated with focal adhesions, whereas p55associates with the mitotic spindle(PMID: 9584194).
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