CoraLite® Plus 488-conjugated PGC1a Monoclonal antibody CL488-66369 proteintech
$479.00
In stock
SKU
CL488-66369
| Catalog Number | CL488-66369 |
| Synonyms | LEM6, Ligand effect modulator 6, PGC 1 alpha, PGC 1(alpha), PGC 1v, PGC1, PGC1A, PGC-1α, PPAR gamma coactivator 1 alpha, PPARGC 1 alpha, PPARGC1, PPARGC1A |
| Host | Mouse |
| Reactivity | human, mouse, rat |
| Form | Liquid |
| Formulation | PBS, Proclin300, BSA, Glycerol |
| Applications | IF/ICC, FC (Intra) |
| Host / Isotype | Mouse / IgG1 |
| Tested Applications — Positive IF/ICC detected in | HeLa cells |
| Tested Applications — Positive FC (Intra) detected in | HeLa cells |
| Tested Applications — Positive FC detected in | HeLa cells |
| Recommended Dilutions — Immunofluorescence (IF)/ICC | IF/ICC : 1:200-1:800 |
| Recommended Dilutions — Flow Cytometry (FC) (INTRA) | FC (INTRA) : 0.20 ug per 10^6 cells in a 100 µl suspension |
| Positive IF/ICC detected in | HeLa cells |
| Positive FC (Intra) detected in | HeLa cells |
| Positive FC detected in | HeLa cells |
| Immunofluorescence (IF)/ICC | IF/ICC : 1:200-1:800 |
| Flow Cytometry (FC) (INTRA) | FC (INTRA) : 0.20 ug per 10^6 cells in a 100 µl suspension |
| Flow Cytometry (FC) | FC : 0.20 ug per 10^6 cells in a 100 µl suspension |
| Tested Reactivity | human, mouse, rat |
| Cited Reactivity | human, mouse |
| Class | Monoclonal |
| Type | Antibody |
| Immunogen | Peptide Predict reactive species |
| Full Name | peroxisome proliferator-activated receptor gamma, coactivator 1 alpha |
| Calculated Molecular Weight | 91 kDa |
| GenBank Accession Number | NM_013261 |
| Gene Symbol | PGC1a |
| Gene ID (NCBI) | 10891 |
| RRID | AB_2919318 |
| Conjugate | CoraLite® Plus 488 Fluorescent Dye |
| Excitation/Emission Maxima Wavelengths | 493 nm / 522 nm |
| Excitation Laser | Blue laser (488 nm) |
| Purification Method | Protein G purification |
| UNIPROT ID | Q9UBK2 |
| Storage Buffer | PBS with 50% glycerol, 0.05% Proclin300, 0.5% BSA, pH 7.3. |
| Storage Conditions | Store at -20°C. Avoid exposure to light. Stable for one year after shipment. Aliquoting is unnecessary for -20 o C storage. |
| FC protocol for CL Plus 488 PGC1a antibody CL488-66369 | Download protocol |
| IF protocol for CL Plus 488 PGC1a antibody CL488-66369 | Download protocol |
| mouse | IF Front Immunol Immunometabolic analysis of primary murine group 2 innate lymphoid cells: a robust step-by-step approach Authors - Sai Sakktee Krisna View Article |
| human | IF FEBS Open Bio Metformin promotes mitochondrial integrity through AMPK-signaling in Leber's hereditary optic neuropathy. Authors - Chatnapa Panusatid View Article |
| Citations | 2 |
| Dilutions | IF/ICC : 1:200-1:800 FC (INTRA) : 0.20 ug per 10^6 cells in a 100 µl suspension |
| Isotype | IgG1 |
| Clonality | Monoclonal |
| Clone Number | 1C1B2 |
| Conjugation | CoraLite® Plus 488 |
PPARGC1A, also named as Peroxisome proliferator-activated receptor gamma coactivator 1-alpha, is a 798 amino acid protein, which Contains 1 RRM (RNA recognition motif) domain and localizes in the nucleus. PPARGC1A is transcriptional coactivator for steroid receptors and nuclear receptors. PPARGC1A can regulate key mitochondrial genes that contribute to the program of adaptive thermogenesis and plays an essential role in metabolic reprogramming in response to dietary availability through coordination of the expression of a wide array of genes involved in glucose and fatty acid metabolism. PPARGC1A exists a isoforms in the liver and the molecular weight of it is 77 kDa. Except for a deletion of 127 amino acids at the N terminus, the protein, termed L-PGC-1 α, is identical to PGC-1. Protocols Product Specific Protocols FC protocol for CL Plus 488 PGC1a antibody CL488-66369 Download protocol IF protocol for CL Plus 488 PGC1a antibody CL488-66369 Download protocol Standard Protocols Click here to view our Standard Protocols
Publications
- Immunometabolic analysis of primary murine group 2 innate lymphoid cells: a robust step-by-step approach
Journal: Front Immunol | Authors: Sai Sakktee Krisna | Species: mouse | Application: IF - Metformin promotes mitochondrial integrity through AMPK-signaling in Leber's hereditary optic neuropathy.
Journal: FEBS Open Bio | Authors: Chatnapa Panusatid | Species: human | Application: IF
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