PRC1 Recombinant monoclonal antibody, PBS Only (Capture) 84041-2-PBS proteintech

$699.00
In stock
SKU
84041-2-PBS
Catalog No.SizePrice (USD)
84041-2-PBS-100UG100 μg$699.00
Catalog Number84041-2-PBS
Synonyms241216H2, ASE1
HostRabbit
Reactivityhuman
FormLiquid
FormulationPBS Only
ApplicationsWB, IF/ICC, Cytometric bead array, Indirect ELISA
Host / IsotypeRabbit / IgG
Tested Reactivityhuman
ClassRecombinant
TypeAntibody
ImmunogenCatNo: Ag8028 Product name: Recombinant human PRC1 protein Source: e coli. -derived, PGEX-4T Tag: GST Domain: 154-446 aa of BC003138 Sequence: NQFRQHVTTLRETKASRREEFVSIKRQIILCMEELDHTPDTSFERDVVCEDEDAFCLSLENIATLQKLLRQLEMQKSQNEAVCEGLRTQIRELWDRLQIPEEEREAVATIMSGSKAKVRKALQLEVDRLEELKMQNMKKVIEAIRVELVQYWDQCFYSQEQRQAFAPFCAEDYTESLLQLHDAEIVRLKNYYEVHKELFEGVQKWEETWRLFLEFERKASDPNRFTNRGGNLLKEEKQRAKLQKMLPKLEEELKARIELWEQEHSKAFMVNGQKFMEYVAEQWEMHRLEKERA Predict reactive species
Full Nameprotein regulator of cytokinesis 1
Calculated Molecular Weight72 kDa
Observed Molecular Weight66-72 kDa
GenBank Accession NumberBC003138
Gene SymbolPRC1
Gene ID (NCBI)9055
RRIDAB_3671608
ConjugateUnconjugated
Purification MethodProtein A purification
UNIPROT IDO43663
Storage BufferPBS only, pH 7.3.
Storage ConditionsStore at -80°C.
Citations-
IsotypeIgG
ClonalityRecombinant
Clone Number241216H2
ConjugationUnconjugated

PRC1 (protein regulator of cytokinesis 1) is a microtubule-bundling protein that is involved in cytokinesis. Depletion of PRC1 leads to failed cytokinesis. PRC1 is located in the nucleus during interphase, and becomes associated with mitotic spindles in a highly dynamic manner during mitosis, and localizes to the cell mid-body during cytokinesis. PRC1 is a substrate of CDK1 and it was assumed that CDK1 phosphorylation blocks its activity during metaphase. Three isoforms of PRC1 exist due to the alternative splicing, with predictive molecular weight of 71.6 kDa, 70.2 kDa and 66.2 kDa, respectively.

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