RAB5B Recombinant monoclonal antibody, PBS Only 86951-2-PBS proteintech
$699.00
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SKU
86951-2-PBS
| Catalog Number | 86951-2-PBS |
| Synonyms | EC:3.6.5.2, Ras related protein Rab 5B, Ras-related protein Rab-5B |
| Host | Rabbit |
| Reactivity | human, mouse, rat |
| Form | Liquid |
| Formulation | PBS Only |
| Applications | Indirect ELISA |
| Host / Isotype | Rabbit / IgG |
| Tested Reactivity | human, mouse, rat |
| Class | Recombinant |
| Type | Antibody |
| Immunogen | CatNo: Eg5609 Product name: Recombinant human RAB5B protein Source: mammalian cells -derived, V37 Tag: C-rFc Domain: 1-215 aa of NM_001252036.2 Sequence: MTSRSTARPNGQPQASKICQFKLVLLGESAVGKSSLVLRFVKGQFHEYQESTIGAAFLTQSVCLDDTTVKFEIWDTAGQERYHSLAPMYYRGAQAAIVVYDITNQETFARAKTWVKELQRQASPSIVIALAGNKADLANKRMVEYEEAQAYADDNSLLFMETSAKTAMNVNDLFLAIAKKLPKSEPQNLGGAAGRSRGVDLHEQSQQNKSQCCSN Predict reactive species |
| Full Name | RAB5B, member RAS oncogene family |
| Calculated Molecular Weight | 24 kDa |
| Observed Molecular Weight | 27 kDa |
| GenBank Accession Number | NM_001252036.2 |
| Gene Symbol | RAB5B |
| Gene ID (NCBI) | 5869 |
| Conjugate | Unconjugated |
| Purification Method | Protein A purification |
| UNIPROT ID | P61020-1 |
| Storage Buffer | PBS only, pH 7.3. |
| Storage Conditions | Store at -80°C. |
| Citations | - |
| Isotype | IgG |
| Clonality | Recombinant |
| Clone Number | 252038A8 |
| Conjugation | Unconjugated |
RAB5B (Ras-related protein Rab-5B) belongs to the Rab family. Rab5 is specifically localized to the early compartment and regulates endocytosis (PMID:1516130, PMID:9087439). There are three isoforms of Rab5 namely, Rab5a, Rab5b, and Rab5c present in EE of mammalian cells (PMID:7789520). Recently, we have shown that Rab5a regulates fluid-phase endocytosis whereas receptor-mediated endocytosis is regulated by Rab5b in Leishmania (PMID:27226564).
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