RIMBP2 Polyclonal antibody 15716-1-AP proteintech
$149.00
In stock
SKU
15716-1-AP
| Catalog Number | 15716-1-AP |
| Synonyms | KIAA0318, RBP2, RIM BP2, RIMBP2, RIMS binding protein 2 |
| Host | Rabbit |
| Reactivity | human, mouse, rat |
| Form | Liquid |
| Formulation | PBS, Azide, Glycerol |
| Applications | WB, IHC, ELISA |
| Host / Isotype | Rabbit / IgG |
| Tested Applications — Positive WB detected in | mouse brain tissue, rat brain tissue |
| Tested Applications — Positive IHC detected in | mouse brain tissue Note: suggested antigen retrieval with TE buffer pH 9.0; (*) Alternatively, antigen retrieval may be performed with citrate buffer pH 6.0 |
| Recommended Dilutions — Western Blot (WB) | WB : 1:1000-1:4000 |
| Recommended Dilutions — Immunohistochemistry (IHC) | IHC : 1:50-1:500 |
| Positive WB detected in | mouse brain tissue, rat brain tissue |
| Positive IHC detected in | mouse brain tissue Note: suggested antigen retrieval with TE buffer pH 9.0; (*) Alternatively, antigen retrieval may be performed with citrate buffer pH 6.0 |
| Western Blot (WB) | WB : 1:1000-1:4000 |
| Immunohistochemistry (IHC) | IHC : 1:50-1:500 |
| Tested Reactivity | human, mouse, rat |
| Cited Reactivity | human, mouse |
| Class | Polyclonal |
| Type | Antibody |
| Immunogen | CatNo: Ag8390 Product name: Recombinant human RIMBP2 protein Source: e coli. -derived, PGEX-4T Tag: GST Domain: 1-350 aa of BC007632 Sequence: MNGLATSLGKGQESAIGGSSAIGEYIRPLPQPGDRPEPLSAKPTFLSRSGSARCRSESDMENERNSNTSKQRYSGKVHLCVARYSYNPFDGPNENPEAELPLTAGKYLYVYGDMDEDGFYEGELLDGQRGLVPSNFVDFVQDNESRLASTLGNEQDQNFINHSGIGLEGEHILDLHSPTHIDAGITDNSAGTLDVNIDDIGEDIVPYPRKITLIKQLAKSVIVGWEPPAVPPGWGTVSSYNVLVDKETRMNLTLGSRTKALIEKLNMAACTYRISVQCVTSRGSSDELQCTLLVGKDVVVAPSHLRVDNITQISAQLSWLPTNSNYSHVIFLNEEEFDIVKAARYKYQFF Predict reactive species |
| Full Name | RIMS binding protein 2 |
| Calculated Molecular Weight | 116 kDa |
| Observed Molecular Weight | 120-150 kDa |
| GenBank Accession Number | BC007632 |
| Gene Symbol | RIMBP2 |
| Gene ID (NCBI) | 23504 |
| RRID | AB_2878173 |
| Conjugate | Unconjugated |
| Purification Method | Antigen affinity purification |
| UNIPROT ID | O15034 |
| Storage Buffer | PBS with 0.02% sodium azide and 50% glycerol, pH 7.3. |
| Storage Conditions | Store at -20°C. Stable for one year after shipment. Aliquoting is unnecessary for -20 o C storage. 20ul sizes contain 0.1% BSA. |
| IHC protocol for RIMBP2 antibody 15716-1-AP | Download protocol |
| WB protocol for RIMBP2 antibody 15716-1-AP | Download protocol |
| mouse | WB Elife Functional hierarchy among different Rab27 effectors involved in secretory granule exocytosis Authors - Kunli Zhao View Article |
| human | WB Cancer Gene Ther N6-methyladenosine modification of RIMS binding protein 2 promotes head and neck squamous cell carcinoma proliferation and radiotherapy tolerance through endoplasmic reticulum stress Authors - Xinyu Sun View Article |
| Citations | 3 |
| Dilutions | WB : 1:1000-1:4000 IHC : 1:50-1:500 |
| Isotype | IgG |
| Clonality | Polyclonal |
| Clone Number | - |
| Conjugation | Unconjugated |
The presynaptic active zone mediates synaptic vesicle exocytosis at a synapse. RIM proteins are active zone scaffolding molecules that--among others--mediate vesicle priming and directly or indirectly interact with most other essential presynaptic proteins. RIMBP2 encodes RIMS-binding protein 2 belonging to RIMBP family. RIMBP2 is supposed to be localized at cell membrane especially synaptic plasma membrane. By interacting with RIMS1, RIMS2, CACNA1D and CACNA1B via the SH3 domains, RIMBP2 mediates synaptic transmission as bifunctional linker. Protocols Product Specific Protocols IHC protocol for RIMBP2 antibody 15716-1-AP Download protocol WB protocol for RIMBP2 antibody 15716-1-AP Download protocol Standard Protocols Click here to view our Standard Protocols
Publications
- Exophilin-8 assembles secretory granules for exocytosis in the actin cortex via interaction with RIM-BP2 and myosin-VIIa.
Journal: Elife | Authors: Fushun Fan KD Validated | Species: mouse | Application: WB - Functional hierarchy among different Rab27 effectors involved in secretory granule exocytosis
Journal: Elife | Authors: Kunli Zhao | Species: mouse | Application: WB - N6-methyladenosine modification of RIMS binding protein 2 promotes head and neck squamous cell carcinoma proliferation and radiotherapy tolerance through endoplasmic reticulum stress
Journal: Cancer Gene Ther | Authors: Xinyu Sun | Species: human | Application: WB
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