SLU7 Polyclonal antibody 12050-1-AP proteintech
$149.00
In stock
SKU
12050-1-AP
| Catalog Number | 12050-1-AP |
| Synonyms | 9G8, hSlu7, Pre mRNA splicing factor SLU7, SLU7 |
| Host | Rabbit |
| Reactivity | human, mouse, rat |
| Form | Liquid |
| Formulation | PBS, Azide, Glycerol |
| Applications | WB, IHC, IF, RIP, ELISA |
| Applications | WB, IHC, ELISA |
| Host / Isotype | Rabbit / IgG |
| Tested Applications — Positive WB detected in | Jurkat cells, HeLa cells, mouse colon tissue, K-562 cells, Y79 cells |
| Tested Applications — Positive IHC detected in | mouse pancreas tissue, human colon cancer tissue, rat pancreas tissue, rat stomach tissue Note: suggested antigen retrieval with TE buffer pH 9.0; (*) Alternatively, antigen retrieval may be performed with citrate buffer pH 6.0 |
| Recommended Dilutions — Western Blot (WB) | WB : 1:500-1:2000 |
| Recommended Dilutions — Immunohistochemistry (IHC) | IHC : 1:50-1:500 |
| Positive WB detected in | Jurkat cells, HeLa cells, mouse colon tissue, K-562 cells, Y79 cells |
| Positive IHC detected in | mouse pancreas tissue, human colon cancer tissue, rat pancreas tissue, rat stomach tissue Note: suggested antigen retrieval with TE buffer pH 9.0; (*) Alternatively, antigen retrieval may be performed with citrate buffer pH 6.0 |
| Western Blot (WB) | WB : 1:500-1:2000 |
| Immunohistochemistry (IHC) | IHC : 1:50-1:500 |
| Tested Reactivity | human, mouse, rat |
| Cited Reactivity | human, mouse |
| Class | Polyclonal |
| Type | Antibody |
| Immunogen | CatNo: Ag2680 Product name: Recombinant human SLU7 protein Source: e coli. -derived, PGEX-4T Tag: GST Domain: 1-301 aa of BC010634 Sequence: MSATVVDAVNAAPLSGSKEMSLEEPKKMTREDWRKKKELEEQRKLGNAPAEVDEEGKDINPHIPQYISSVPWYIDPSKRPTLKHQRPQPEKQKQFSSSGEWYKRGVKENSVITKYRKGACENCGAMTHKKKDCFERPRRVGAKFTGTNIAPDEHVQPQLMFDYDGKRDRWNGYNPEEHMKIVEEYAKVDLAKRTLKAQKLQEELASGKLVEQANSPKHQWGEEEPNSQTEKDHNSEDEDEDKYADDIDMPGQNFDSKRRITVRNLRIREDIAKYLRNLDPNSAYYDPKTRAMRENPYANAG Predict reactive species |
| Full Name | SLU7 splicing factor homolog (S. cerevisiae) |
| Calculated Molecular Weight | 586 aa, 68 kDa |
| Observed Molecular Weight | 68 kDa |
| GenBank Accession Number | BC010634 |
| Gene Symbol | SLU7 |
| Gene ID (NCBI) | 10569 |
| RRID | AB_10663102 |
| Conjugate | Unconjugated |
| Purification Method | Antigen affinity purification |
| UNIPROT ID | O95391 |
| Storage Buffer | PBS with 0.02% sodium azide and 50% glycerol, pH 7.3. |
| Storage Conditions | Store at -20°C. Stable for one year after shipment. Aliquoting is unnecessary for -20 o C storage. 20ul sizes contain 0.1% BSA. |
| IHC protocol for SLU7 antibody 12050-1-AP | Download protocol |
| WB protocol for SLU7 antibody 12050-1-AP | Download protocol |
| human | WB Mol Cell Spliceosomal proofreading factors safeguard 3' splice-site fidelity and prevent proteotoxicity and inflammation Authors - Fangshu Li View Article |
| human,mouse | WB,IHC,IF Adv Sci (Weinh) G3BP1 and SLU7 Jointly Promote Immune Evasion by Downregulating MHC-I via PI3K/Akt Activation in Bladder Cancer Authors - Xianchong Zheng KD Validated View Article |
| Citations | 4 |
| Dilutions | WB : 1:500-1:2000 IHC : 1:50-1:500 |
| Isotype | IgG |
| Clonality | Polyclonal |
| Clone Number | - |
| Conjugation | Unconjugated |
Pre-mRNA splicing occurs in two sequential transesterification steps. SLU7 is a splicing factor that has been found to be essential during the second catalytic step in the pre-mRNA splicing process. It associates with the spliceosome and contains a zinc knuckle motif that is found in other splicing factors and is involved in protein-nucleic acid and protein-protein interactions. Protocols Product Specific Protocols IHC protocol for SLU7 antibody 12050-1-AP Download protocol WB protocol for SLU7 antibody 12050-1-AP Download protocol Standard Protocols Click here to view our Standard Protocols
Publications
- NAA50-mediated SLU7 stabilization promotes cisplatin resistance in bladder cancer via regulating MAP3K3 mRNA nuclear export and p38 MAPK activation.
Journal: Cell Oncol (Dordr) | Authors: Benlin Wang - A novel polypeptide CAPG-171aa encoded by circCAPG plays a critical role in triple-negative breast cancer
Journal: Mol Cancer | Authors: Runjie Song | Species: human | Application: RIP - G3BP1 and SLU7 Jointly Promote Immune Evasion by Downregulating MHC-I via PI3K/Akt Activation in Bladder Cancer
Journal: Adv Sci (Weinh) | Authors: Xianchong Zheng KD Validated | Species: human,mouse | Application: WB,IHC,IF - Spliceosomal proofreading factors safeguard 3' splice-site fidelity and prevent proteotoxicity and inflammation
Journal: Mol Cell | Authors: Fangshu Li | Species: human | Application: WB
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