CoraLite®594-conjugated TLR8 Monoclonal antibody CL594-67317 proteintech
$479.00
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CL594-67317
| Catalog Number | CL594-67317 |
| Synonyms | CD288, TLR8, toll like receptor 8 |
| Host | Mouse |
| Reactivity | Human and More (1) |
| Reactivity | human, mouse |
| Form | Liquid |
| Formulation | PBS, Proclin300, BSA, Glycerol |
| Applications | IF-P |
| Host / Isotype | Mouse / IgG1 |
| Tested Applications — Positive IF-P detected in | human tonsillitis tissue |
| Recommended Dilutions — Immunofluorescence (IF)-P | IF-P : 1:50-1:500 |
| Positive IF-P detected in | human tonsillitis tissue |
| Immunofluorescence (IF)-P | IF-P : 1:50-1:500 |
| Tested Reactivity | Human |
| Cited Reactivity | mouse |
| Class | Monoclonal |
| Type | Antibody |
| Immunogen | CatNo: Ag16566 Product name: Recombinant human TLR8 protein Source: e coli. -derived, PET28a Tag: 6*His Domain: 261-610 aa of BC101075 Sequence: FNAPFPCVPCDGGASINIDRFAFQNLTQLRYLNLSSTSLRKINAAWFKNMPHLKVLDLEFNYLVGEIASGAFLTMLPRLEILDLSFNYIKGSYPQHINISRNFSKLLSLRALHLRGYVFQELREDDFQPLMQLPNLSTINLGINFIKQIDFKLFQNFSNLEIIYLSENRISPLVKDTRQSYANSSSFQRHIRKRRSTDFEFDPHSNFYHFTRPLIKPQCAAYGKALDLSLNSIFFIGPNQFENLPDIACLNLSANSNAQVLSGTEFSAIPHVKYLDLTNNRLDFDNASALTELSDLEVLDLSYNSHYFRIAGVTHHLEFIQNFTNLKVLNLSHNNIYTLTDKYNLESKSL Predict reactive species |
| Full Name | toll-like receptor 8 |
| Calculated Molecular Weight | 1041 aa, 120 kDa |
| Observed Molecular Weight | 120 kDa |
| GenBank Accession Number | BC101075 |
| Gene Symbol | TLR8 |
| Gene ID (NCBI) | 51311 |
| RRID | AB_2920112 |
| Conjugate | CoraLite®594 Fluorescent Dye |
| Excitation/Emission Maxima Wavelengths | 588 nm / 604 nm |
| Excitation Laser | Yellow-Green Laser (561 nm) |
| Purification Method | Protein G purification |
| UNIPROT ID | Q9NR97 |
| Storage Buffer | PBS with 50% glycerol, 0.05% Proclin300, 0.5% BSA, pH 7.3. |
| Storage Conditions | Store at -20°C. Avoid exposure to light. Stable for one year after shipment. Aliquoting is unnecessary for -20 o C storage. |
| IF protocol for CL594 TLR8 antibody CL594-67317 | Download protocol |
| mouse | IF Function (Oxf) Loss of STIM1 and STIM2 in Salivary Glands Disrupts ANO1 Function but Does Not Induce Sjogren's Disease Authors - Ga-Yeon Son View Article |
| Citations | 1 |
| Dilutions | IF-P : 1:50-1:500 |
| Isotype | IgG1 |
| Clonality | Monoclonal |
| Clone Number | 3B6A4 |
| Conjugation | CoraLite®594 |
Toll-like receptors (TLRs) are a group of pathogen recognition receptors (PRRs) that can be divided into two subfamilies depending on their subcellular localization(PMID: 32268138). Toll-like receptor 8 (TLR8), a sensor for pathogen-derived single-stranded RNA (ssRNA), binds to uridine (Uri) and ssRNA to induce defense responses (PMID:30535046). TLR8 proteins were expressed in spleen, epididymal sperm, testicular sperm cells, and Leydig cells but were weak in Sertoli cells. It can identify two isoforms,120 and 122 kDa. Protocols Product Specific Protocols IF protocol for CL594 TLR8 antibody CL594-67317 Download protocol Standard Protocols Click here to view our Standard Protocols
Publications
- Loss of STIM1 and STIM2 in Salivary Glands Disrupts ANO1 Function but Does Not Induce Sjogren's Disease
Journal: Function (Oxf) | Authors: Ga-Yeon Son | Species: mouse | Application: IF
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