TRPM7 Recombinant monoclonal antibody 84324-1-RR proteintech
$149.00
In stock
SKU
84324-1-RR
| Catalog Number | 84324-1-RR |
| Synonyms | 241191G7, CHAK, CHAK1, Channel kinase 1, Channel-kinase 1 |
| Host | Rabbit |
| Reactivity | human |
| Form | Liquid |
| Formulation | PBS, Azide, Glycerol |
| Applications | WB, IHC, ELISA |
| Host / Isotype | Rabbit / IgG |
| Tested Applications — Positive WB detected in | HeLa cells, HUVEC cells |
| Tested Applications — Positive IHC detected in | mouse brain tissue Note: suggested antigen retrieval with TE buffer pH 9.0; (*) Alternatively, antigen retrieval may be performed with citrate buffer pH 6.0 |
| Recommended Dilutions — Western Blot (WB) | WB : 1:1000-1:6000 |
| Recommended Dilutions — Immunohistochemistry (IHC) | IHC : 1:50-1:500 |
| Positive WB detected in | HeLa cells, HUVEC cells |
| Positive IHC detected in | mouse brain tissue Note: suggested antigen retrieval with TE buffer pH 9.0; (*) Alternatively, antigen retrieval may be performed with citrate buffer pH 6.0 |
| Western Blot (WB) | WB : 1:1000-1:6000 |
| Immunohistochemistry (IHC) | IHC : 1:50-1:500 |
| Tested Reactivity | human |
| Class | Recombinant |
| Type | Antibody |
| Immunogen | Peptide Predict reactive species |
| Full Name | transient receptor potential cation channel, subfamily M, member 7 |
| Calculated Molecular Weight | 213 kDa |
| Observed Molecular Weight | 220 kDa |
| GenBank Accession Number | NM_017672 |
| Gene Symbol | TRPM7 |
| Gene ID (NCBI) | 54822 |
| RRID | AB_3671866 |
| Conjugate | Unconjugated |
| Purification Method | Protein A purfication |
| UNIPROT ID | Q96QT4 |
| Storage Buffer | PBS with 0.02% sodium azide and 50% glycerol, pH 7.3. |
| Storage Conditions | Store at -20°C. Stable for one year after shipment. Aliquoting is unnecessary for -20 o C storage. 20ul sizes contain 0.1% BSA. |
| IHC protocol for TRPM7 antibody 84324-1-RR | Download protocol |
| WB protocol for TRPM7 antibody 84324-1-RR | Download protocol |
| Citations | - |
| Dilutions | WB : 1:1000-1:6000 IHC : 1:50-1:500 |
| Isotype | IgG |
| Clonality | Recombinant |
| Clone Number | 241191G7 |
| Conjugation | Unconjugated |
Transient receptor potential melastatin 7 (TRPM7), along with the closely related TRPM6, are unique channels that have dual operations: cation permeability and kinase activity. In contrast to the limited tissue distribution of TRPM6, TRPM7 is widely expressed among tissues and is therefore implicated in a variety of cellular functions physiologically and pathophysiologically. The discovery of TRPM7's unique structure imparting dual ion channel and kinase activities shed light onto novel and peculiar biological functions, such as Mg2+ homeostasis, cellular Ca2+ flickering, and even intranuclear transcriptional regulation by a cleaved kinase domain translocated to nuclei. Protocols Product Specific Protocols IHC protocol for TRPM7 antibody 84324-1-RR Download protocol WB protocol for TRPM7 antibody 84324-1-RR Download protocol Standard Protocols Click here to view our Standard Protocols
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