VILIP1 Monoclonal antibody 67134-1-Ig proteintech
$149.00
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SKU
67134-1-Ig
| Catalog Number | 67134-1-Ig |
| Synonyms | VILIP 1, VILIP-1, VSNL1, 2C6C3, Hippocalcin like protein 3 |
| Host | Mouse |
| Reactivity | human, mouse, rat, pig |
| Form | Liquid |
| Formulation | PBS, Azide, Glycerol |
| Applications | WB, IHC, ELISA |
| Host / Isotype | Mouse / IgG1 |
| Tested Applications — Positive WB detected in | human brain tissue, rat brain tissue, mouse brain tissue |
| Tested Applications — Positive IHC detected in | mouse brain tissue Note: suggested antigen retrieval with TE buffer pH 9.0; (*) Alternatively, antigen retrieval may be performed with citrate buffer pH 6.0 |
| Recommended Dilutions — Western Blot (WB) | WB : 1:1000-1:6000 |
| Recommended Dilutions — Immunohistochemistry (IHC) | IHC : 1:150-1:600 |
| Positive WB detected in | human brain tissue, rat brain tissue, mouse brain tissue |
| Positive IHC detected in | mouse brain tissue Note: suggested antigen retrieval with TE buffer pH 9.0; (*) Alternatively, antigen retrieval may be performed with citrate buffer pH 6.0 |
| Western Blot (WB) | WB : 1:1000-1:6000 |
| Immunohistochemistry (IHC) | IHC : 1:150-1:600 |
| Tested Reactivity | human, mouse, rat, pig |
| Cited Reactivity | human |
| Class | Monoclonal |
| Type | Antibody |
| Immunogen | CatNo: Ag4923 Product name: Recombinant human VSNL1 protein Source: e coli. -derived, T-HIS Tag: 6*His Domain: 1-191 aa of BC022012 Sequence: MGKQNSKLAPEVMEDLVKSTEFNEHELKQWYKGFLKDCPSGRLNLEEFQQLYVKFFPYGDASKFAQHAFRTFDKNGDGTIDFREFICALSITSRGSFEQKLNWAFNMYDLDGDGKITRVEMLEIIEAIYKMVGTVIMMKMNEDGLTPEQRVDKIFSKMDKNKDDQITLDEFKEAAKSDPSIVLLLQCDIQK Predict reactive species |
| Full Name | visinin-like 1 |
| Calculated Molecular Weight | 22 kDa |
| Observed Molecular Weight | 20 kDa |
| GenBank Accession Number | BC022012 |
| Gene Symbol | VSNL1 |
| Gene ID (NCBI) | 7447 |
| RRID | AB_2882433 |
| Conjugate | Unconjugated |
| Purification Method | Protein G purification |
| UNIPROT ID | P62760 |
| Storage Buffer | PBS with 0.02% sodium azide and 50% glycerol, pH 7.3. |
| Storage Conditions | Store at -20°C. Stable for one year after shipment. Aliquoting is unnecessary for -20 o C storage. 20ul sizes contain 0.1% BSA. |
| IHC protocol for VILIP1 antibody 67134-1-Ig | Download protocol |
| WB protocol for VILIP1 antibody 67134-1-Ig | Download protocol |
| human | IHC Biomedicines Characteristic Analysis of Featured Genes Associated with Cholangiocarcinoma Progression Authors - Qigu Yao View Article |
| Citations | 1 |
| Dilutions | WB : 1:1000-1:6000 IHC : 1:150-1:600 |
| Isotype | IgG1 |
| Clonality | Monoclonal |
| Clone Number | 2C6C3 |
| Conjugation | Unconjugated |
Visinin-like protein 1 (VILIP1) is also named VLP-1, hippocalcin-like protein 3 (HLP3), VSNL1 and VISL1. The neuronal calcium sensor protein VILIP1 forms a complex with neurotransmitter-gated P2X2 receptors, functions as a channel regulator, and likely binds more tightly to P2X2 receptors in an activation- and calcium-dependent manner (PMID: 18922787). VILIP1 is widely expressed and involved in physiological and disease processes throughout the body, including tumor formation (PMID: 17311005, PMID: 18301774). VILIP1 is localized primarily in the rat hippocampus, where it controls neuronal excitability important for learning and memory (PMID: 18440708, PMID: 15336574). In particular, VILIP1 binds to the α-subunit of the α4β2 nicotinic acetylcholine receptor (nAChR), which promotes its surface expression and trafficking in oocytes and hippocampal neurons (PMID: 1220248, PMID: 19063970). Protocols Product Specific Protocols IHC protocol for VILIP1 antibody 67134-1-Ig Download protocol WB protocol for VILIP1 antibody 67134-1-Ig Download protocol Standard Protocols Click here to view our Standard Protocols
Publications
- Characteristic Analysis of Featured Genes Associated with Cholangiocarcinoma Progression
Journal: Biomedicines | Authors: Qigu Yao | Species: human | Application: IHC
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