| Catalog Number | PK30018 |
| Synonyms | United States |
| Reactivity | Target Dependent |
| Applications | Target Dependent |
| Host / Isotype | Rabbit/Mouse |
| Antigen | Catalog No. Host, clonality Tested Reactivity Applications Volume |
| m6A | 68055-1-Ig Mouse monoclonal H, M, R, Pg WB, IP, IF, RIP, IHC, ELISA, Dot Blot 20 uL |
| METTL3 | 80323-1-RR Rabbit monoclonal H, M, R WB, IF, IHC, ELISA 20 uL |
| METTL14 | 80790-1-RR Rabbit monoclonal H, M WB, IHC, ELISA 20 uL |
| WTAP | 60188-1-Ig Mouse monoclonal H, M, R, Dr WB, IP, IF, FC, RIP, IHC, ELISA 20 uL |
| FTO | 81471-1-RR Rabbit monoclonal H WB, IF, IHC, ELISA 20 uL |
| ALKBH5 | 67811-1-Ig Mouse monoclonal H, M, R WB, IHC, ELISA 20 uL |
| YTHDF1 | 66745-1-Ig Mouse monoclonal H, M, R, Pg WB, IP, IF, IHC, CoIP, ELISA 20 uL |
| YTHDF2 | 81340-1-RR Rabbit monoclonal H, M, R WB, IP, IF, IHC, CoIP, ELISA 20 uL |
| Range | {{ptg:compareRange}} |
| Test | 20T, 100T, 500T |
m6A (N6-methyladenosine) is the most abundant modification in mammalian mRNA. This modification is initiated by the m6A methylatransferases (writers) such as METTL3, METTL14, and WTAP. m6A modifications can be reversed by demethylases (erasers) such as FTO and ALKBH5. The stability of m6A-modified mRNA is regulated by YTHDF reader proteins, which recognize m6A and reduce the stability of target transcripts. m6A and its regulatory proteins play critical roles in cancer pathogenesis and progression. Standard Protocols Click here to view our standard protocols for various applications including WB, IP, IHC, IF, FC, and ELISA. Cited in Article as PK30018, m6A Essentials Antibody Kit, Proteintech, IL, USA Documentation Datasheet m6A Essentials Antibody Kit Datasheet