Human/Cynomolgus Monkey PCSK9 ELISA Kit KE00278 proteintech
$299.00
In stock
SKU
KE00278
| Product name | Human/Cynomolgus Monkey PCSK9 ELISA Kit |
| Synonyms | EC:3.4.21.-, FH3, HCHOLA3, LDLCQ1, NARC 1 |
| Reactivity | Human/Cynomolgus Monkey |
| Host / Isotype | United States |
| Tests | 1 X 96 well plate |
| Sample type | Serum,Plasma,Cell culture supernatants,Cell lysates |
| Assay type | Sandwich |
| Sensitivity | 2.8 pg/mL |
| Range | 31.25-2000 pg/mL |
| Tested applications | Sandwich ELISA |
| Gene ID (NCBI) | 255738 |
| Sample Type | Average Range |
| Human serum | 111% 102%-128% |
| Cell culture supernatants | 102% 80%-115% |
| Cell lysates | 105% 92%-120% |
| Cynomolgus monkey serum | 97% 88%-110% |
| Sample | n mean ( pg/mL ) SD CV% |
| 1 | 24 891.8 21.6 2.4 |
| 2 | 24 206.7 5.6 2.7 |
| 3 | 24 48.8 4.0 8.1 |
| Storage Instructions | All the reagents are stored at 2-8℃ for 6 months or -20℃ for 12 months. Refer to the protocol for further storage instructions. |
| human | cell culture supernatants Cancer Commun (Lond) Lipid metabolism reprograming by SREBP1-PCSK9 targeting sensitizes pancreatic cancer to immunochemotherapy Authors - Mengyi Lao View Article |
PCSK9, also named as NARC1 and PC9, belongs to the peptidase S8 family. PCSK9 is expressed and secreted by several tissues but principally by the liver, small intestines, and kidney (PMID 28587771). It may be implicated in the differentiation of cortical neurons and may play a role in cholesterol homeostasis. PCSK9 is a regulator of the LDL receptor and plasma cholesterol concentrations (PMID: 26293463). Properties Storage Instructions All the reagents are stored at 2-8℃ for 6 months or -20℃ for 12 months. Refer to the protocol for further storage instructions. Synonyms EC:3.4.21.-, FH3, HCHOLA3, LDLCQ1, NARC 1 FAQ 1、I have limited sample diluent. How should I handle samples requiring high dilution factors? Answer: We recommend performing a serial dilution. For example, if human serum requires a 1,000,000-fold dilution, you can use a three-step 100× dilution method as follows: Step 1: Take 2 uL of human serum and add it to 198 uL of sample diluent, mix thoroughly to obtain a 100-fold diluted sample. Step 2: Take 2 uL of the 100-fold diluted sample and add it to 198 uL of sample diluent, mix thoroughly to obtain a 10,000-fold diluted sample. Step 3: Take 2 uL of the 10,000-fold diluted sample and add it to 198 uL of sample diluent, mix thoroughly to obtain a 1,000,000-fold diluted sample. If further dilution is required, additional serial steps can be used. We do not recommend using any other solutions or water for dilution, except for the sample diluent we suggest. If your sample diluent is still insufficient, please contact our customer service for more sample diluent.
Publications
- Inhibition of PCSK9 protects against myocardial ischemia-reperfusion injury by suppressing ferroptosis via negative regulation of the P65/MMP9 pathway.
Journal: Sci Rep | Authors: Jianan Xu - 2'-Ribose-modified nucleotides: A strategy for reducing off-target effects of oligonucleotide drugs.
Journal: Mol Ther Nucleic Acids | Authors: Honglei Zhang | Species: human | Application: Serum - Hepatocyte-Targeted Cyclic Peptide LYTACs for PCSK9 Degradation and LDL Cholesterol Metabolic Regulation.
Journal: ACS Chem Biol | Authors: Bin Feng | Species: human | Application: cell culture supernatants - Engineered extracellular vesicles as nanosponges for lysosomal degradation of PCSK9
Journal: Mol Ther | Authors: Chen Wang | Species: human | Application: cell culture supernatants - Large-scale proteomic analysis of aqueous humor from patients with primary open angle and exfoliation glaucoma.
Journal: Sci Rep | Authors: Naofumi Funagura | Species: human | Application: Serum, Plasma, cell culture supernatants, Cell lys - Lipid metabolism reprograming by SREBP1-PCSK9 targeting sensitizes pancreatic cancer to immunochemotherapy
Journal: Cancer Commun (Lond) | Authors: Mengyi Lao | Species: human | Application: cell culture supernatants
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