Human OATP1B1/SLCO1B1 ELISA Kit KE00588 proteintech
$299.00
In stock
SKU
KE00588
| Product name | Human OATP1B1/SLCO1B1 ELISA Kit |
| Synonyms | SLCO1B1, LST 1, LST1, OATP 2, OATP C |
| Reactivity | Human |
| Host / Isotype | United States |
| Tests | 1 X 96 well plate |
| Sample type | Serum, Plasma |
| Assay type | Sandwich |
| Sensitivity | 0.01 ng/mL |
| Range | 0.156-10 ng/mL |
| Tested applications | Sandwich ELISA |
| Gene ID (NCBI) | 10599 |
| Sample Type | Average Range |
| Human serum | 114% 109%-123% |
| Sample | n mean ( ng/mL ) SD CV% |
| 1 | 16 4.90 0.41 8.43 |
| 2 | 16 1.14 0.08 6.64 |
| 3 | 16 0.57 0.06 10.19 |
| Storage Instructions | All the reagents are stored at 2-8℃ for 6 months or -20℃ for 12 months. Refer to the protocol for further storage instructions. |
A membrane-bound sodium-independent organic anion transporter protein (OATP1B1), encoded by the SLCO1B1 gene (Solute Carrier Organic Anion Transporter Family Member 1B1), is a critical hepatic uptake transporter that plays a pivotal role in the pharmacokinetics and pharmacodynamics of numerous endogenous compounds and xenobiotics. OATP1B1 is expressed predominantly on the basolateral membrane of hepatocytes, where it mediates active intracellular hepatic transport of various anionic compounds. Polymorphisms in the gene encoding this protein are associated with impaired transporter function. Properties Storage Instructions All the reagents are stored at 2-8℃ for 6 months or -20℃ for 12 months. Refer to the protocol for further storage instructions. Synonyms SLCO1B1, LST 1, LST1, OATP 2, OATP C FAQ 1、I have limited sample diluent. How should I handle samples requiring high dilution factors? Answer: We recommend performing a serial dilution. For example, if human serum requires a 1,000,000-fold dilution, you can use a three-step 100× dilution method as follows: Step 1: Take 2 uL of human serum and add it to 198 uL of sample diluent, mix thoroughly to obtain a 100-fold diluted sample. Step 2: Take 2 uL of the 100-fold diluted sample and add it to 198 uL of sample diluent, mix thoroughly to obtain a 10,000-fold diluted sample. Step 3: Take 2 uL of the 10,000-fold diluted sample and add it to 198 uL of sample diluent, mix thoroughly to obtain a 1,000,000-fold diluted sample. If further dilution is required, additional serial steps can be used. We do not recommend using any other solutions or water for dilution, except for the sample diluent we suggest. If your sample diluent is still insufficient, please contact our customer service for more sample diluent.
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